Hands-On Clinical Data Manager, Gene Therapy

Encoded Therapeutics; United States; On-site; USD 95,000 - 135,000; Full time

Benefits offered by this job

Stock option grants

PTO, holidays, and sick time

Parental leave

401k plan with company contributions

Medical, dental, vision benefits

Job summary

Encoded Therapeutics is seeking a hands-on Clinical Data Manager to drive daily data management across gene therapy programs. You will manage data flow, perform discrepancy handling, and coordinate external data reconciliation with vendors.

This role emphasizes technical execution and documentation rather than site-facing operations. The ideal candidate has 4+ years in clinical data management, strong EDC experience (Medrio/Medidata RAVE), and solid knowledge of GCP and CDISC standards.

Qualifications

• BS/BA or MS in a scientific, health-related, or computational field with 4+ years of hands-on clinical data management experience.
• Experience managing day-to-day CDM lifecycle including data cleaning and multi-vendor reconciliation.
• Strong proficiency with EDC systems (Medrio/Medidata RAVE) and data review tools.

Responsibilities

• Serve as primary hands-on Data Manager for multiple studies, driving data flow and discrepancy management.
• Own external data reconciliation workstreams, tracking and resolving cross-vendor data discrepancies.
• Review TFL specifications and listings with biostatistics to ensure data support and auditability.
• Write and execute UAT plans for databases, CRFs, and data tools, capturing objective evidence.

Skills

Clinical Data Management

EDC systems

Data Cleaning

CDISC standards

UAT planning

Education

BS/BA or MS in science

Tools

Medrio

Medidata RAVE

Job description

Encoded Therapeutics is seeking a hands-on Clinical Data Manager to drive daily data management across gene therapy programs. You will manage data flow, perform discrepancy handling, and coordinate external data reconciliation with vendors.

This role emphasizes technical execution and documentation rather than site-facing operations. The ideal candidate has 4+ years in clinical data management, strong EDC experience (Medrio/Medidata RAVE), and solid knowledge of GCP and CDISC standards.