Global Supply Chain & Launch Readiness Director

Structure Therapeutics Inc.; South San Francisco (CA); On-site; USD 248,000 - 305,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401k match

Unlimited PTO

Winter shutdown

Job summary

Structure Therapeutics Inc. is seeking a Senior Director of Commercial Supply Chain to lead end-to-end planning for late‑stage clinical and commercial programs.

You’ll drive S&OP/COP, demand forecasting, inventory optimization, and risk management across a global network to ensure uninterrupted patient supply. The role requires 15+ years in pharma/biotech supply chains, deep experience with small molecules, and strong leadership across cross‑functional teams.

Qualifications

• Bachelor’s degree in Supply Chain, Engineering, Chemistry, or related discipline required; MBA preferred.
• 15+ years of experience in supply chain management within the pharmaceutical or biotech industry.
• Deep expertise in small molecule manufacturing and oral solid dose (OSD) products/supply chains.
• Deep expertise in supply chain planning, S&OP/COP, and inventory management.
• Proven experience in launch planning and commercialization support.
• Experience with global outsourced supply chains and CDMO networks.
• Strong knowledge of GMP regulations, validation, CPV, and quality systems.
• Experience working with global manufacturing networks and international CDMOs across multiple time zones.
• Expertise in supply chain planning systems and ERP implementations.
• Experience with supply chain integration, production planning, and capacity management.
• Strong knowledge of logistics, distribution, and cold chain requirements.
• Demonstrated experience in risk management and supply chain resilience.
• Excellent leadership, communication, and cross‑functional collaboration skills.
• Ability to operate effectively in a fast‑paced, matrixed, and virtual organization.
• Strategic thinker with strong execution capabilities.

Responsibilities

• Define and execute global supply chain strategies to support clinical development, commercialization, and lifecycle management.
• Lead end-to-end S&OP and C&OP processes.
• Ensure alignment of demand forecasts with manufacturing and supply capabilities.
• Provide strategic input into supply chain network design, long‑term capacity planning, and budget development.
• Collaborate with Clinical Operations, Commercial, and CMC teams to develop accurate demand forecasts.
• Lead demand and supply balancing activities across all supply chain echelons.
• Establish processes to continuously refine forecasts and improve planning accuracy.
• Ensure alignment of demand signals with production and procurement plans.
• Define and manage inventory strategies across the global network.
• Establish safety stock levels to mitigate supply risk.
• Monitor inventory performance, including turns, expiry risk, and working capital.
• Drive optimization of inventory levels to balance service, cost, and risk.
• Lead supply chain planning for product launches, including scenario planning and risk mitigation.
• Ensure readiness of supply chain systems, processes, and inventory to support successful launches.
• Partner with cross‑functional teams to support regulatory milestones and market entry.
• Lead long‑range supply chain network planning to support growth and commercialization.
• Identify and mitigate supply risks through scenario planning, redundancy strategies, and contingency planning.
• Develop and maintain risk management frameworks across the supply chain.
• Support business continuity planning and supply resilience initiatives.
• Lead design, selection, and implementation of supply chain planning tools.
• Ensure effective master data management to support planning and execution.
• Support ERP system implementation and integration for new products and supply chains.
• Drive digital transformation and data‑driven decision making in supply chain operations.
• Oversee storage, shipping, and distribution strategies for clinical and commercial products.
• Ensure compliance with CRT and cold chain requirements.
• Coordinate logistics across global CDMOs, depots, and distribution partners.
• Optimize distribution networks to ensure timely and cost‑effective delivery.
• Partner closely with External Manufacturing, Quality, Regulatory, Clinical Operations, and Commercial teams.
• Serve as a key member of the Manufacturing & Supply Chain and Technical Operations teams.
• Drive continuous improvement initiatives across supply chain processes.
• Ensure alignment across stakeholders to support uninterrupted patient supply.

Skills

Strategic leadership

Cross-functional collaboration

Supply chain planning

S&OP/COP

Inventory management

Risk management

Communication

Leadership

Education

BS in Supply Chain/Engineering/Chemistry

MBA preferred

Tools

ERP systems

CDMO networks

Logistics networks

ERP implementations

Job description

Structure Therapeutics Inc. is seeking a Senior Director of Commercial Supply Chain to lead end-to-end planning for late‑stage clinical and commercial programs.

You’ll drive S&OP/COP, demand forecasting, inventory optimization, and risk management across a global network to ensure uninterrupted patient supply. The role requires 15+ years in pharma/biotech supply chains, deep experience with small molecules, and strong leadership across cross‑functional teams.