Global Safety Leader

Ladders; United States; Remote; USD 125,000 - 150,000; Full time

Benefits offered by this job

Remote work

Travel encouraged

Cross-divisional exposure

Leadership development

Job summary

Ladders, a leader in Pharmaceuticals & Biotech, seeks a Global Safety Leader to oversee medical safety across clinical and post-marketing settings. You will evaluate adverse event data and support benefit-risk decisions while mentoring a global safety team.

This remote US-based role requires FDA/ICH expertise, pharmacovigilance experience, and strong cross-functional collaboration with clinical, regulatory and quality colleagues. Occasional travel may be required.

Qualifications

• MD/DO or equivalent post-graduate medical qualification.
• 5-10 years of clinical or practical experience in a relevant clinical setting.
• 2 years of pharmacovigilance experience in Clinical or Post-Marketing Safety.
• Knowledge of FDA and ICH safety reporting regulations and guidelines.
• Advanced analytical skills and sound medical judgment.

Responsibilities

• Perform and review medical assessments of safety reports and follow-ups.
• Author and approve aggregate safety reports for regulatory agencies.
• Lead safety aspects of clinical trials and evaluate safety monitoring protocols.
• Manage safety signal detection and develop risk management strategies.
• Serve as a safety expert on cross-functional teams for health hazard evaluations.
• Communicate safety and benefit/risk assessments to stakeholders.
• Mentor and onboarding new colleagues.
• Maintain audit readiness for Medical Safety functions.

Skills

Analytical skills

Regulatory knowledge

Medical judgment

Pharmacovigilance

Education

MD/DO or equivalent post-graduate medical qualification

Job description

For our client, we are seeking a Global Safety Leader to join the team of a leader in the Pharmaceuticals & Biotech space. This role will lead medical safety activities across clinical and post-marketing settings, ensuring robust evaluation of adverse event data and strong benefit-risk decision-making. The position partners closely with clinical, regulatory, and cross-functional stakeholders to support compliant safety reporting and risk mitigation. You will also help strengthen safety processes, maintain inspection readiness, and mentor team members within a global medical safety function.

Location: Remote - US based candidates only, no visa sponsorship available

Compensation: $125,000 – $150,000 annually

Responsibilities

• Perform and review medical assessments of safety reports and follow-ups
• Author and approve aggregate safety reports for regulatory agencies
• Lead safety aspects of clinical trials and evaluate safety monitoring protocols
• Manage safety signal detection and develop risk management strategies
• Serve as a safety expert on cross-functional teams for health hazard evaluations
• Communicate safety and benefit/risk assessments to stakeholders
• Mentor and onboarding new colleagues
• Maintain audit readiness for Medical Safety functions

Qualifications

• MD/DO or equivalent post-graduate medical qualification
• 5-10 years of clinical or practical experience in a relevant clinical setting
• 2 years of pharmacovigilance experience in Clinical or Post-Marketing Safety
• Knowledge of FDA and ICH safety reporting regulations and guidelines
• Advanced analytical skills and sound medical judgment

Benefits

• Remote work eligible
• Occasional travel for training and conventions
• Opportunity to engage with multiple corporate divisions
• Development of diverse leadership and analytical skills

Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.