Global Program Clinical Head, Neuroscience (M.D.)

Novartis Farmacéutica; East Hanover (NJ); On-site; USD 261,000 - 485,000; Full time

Job summary

An established industry player is seeking a Global Program Clinical Head for Neuroscience to lead innovative clinical development strategies. This pivotal role involves overseeing the clinical development plan and collaborating with diverse teams to drive projects from pre-clinical phases to market access. The position promises a dynamic environment where your expertise in neuroscience and clinical research will directly impact patient outcomes. Join a forward-thinking company dedicated to advancing medicine and improving lives, where your contributions will be valued in a collaborative and inclusive setting.

Benefits

401(k) eligibility

Paid time off

Medical benefits

Sign-on bonus

Restricted stock units

Qualifications

• 10+ years in clinical research or drug development in industry.
• Strong knowledge of Good Clinical Practice and regulatory processes.

Responsibilities

• Lead clinical development and strategy for Neuroscience.
• Oversee cross-functional teams and manage clinical documentation.

Skills

Clinical Research

Neuroscience Expertise

Leadership Skills

Regulatory Knowledge

Clinical Trial Design

Education

MD or Ph.D.

Job description

Global Program Clinical Head, Neuroscience (M.D.)

Job ID REQ-10046537

Apr 04, 2025

USA

Summary

Onsite
East Hanover, New Jersey

About the role:
With over 60 years of history in neuroscience, Novartis brought landmark therapies to patients with Multiple Sclerosis, Alzheimer’s disease, Parkinson’s Disease, Epilepsy, Depression, and Migraine. We have a world-class pipeline in neuro-inflammation, neurodegeneration, psychiatric, and neuromuscular diseases. Our holistic R&D approach includes cutting-edge molecules, comprehensive approaches to technology, biomarker, and digital therapeutics to propose better solutions for patients worldwide.

As Global Program Clinical Head (GPCH), you are the clinical lead for Neuroscience, leading clinical development and contributing to overall strategy in collaboration with other functions to ensure the development and implementation of the Clinical Development plan. You will lead a cross-functional team of specialists and align early development plans with the overall strategy, oversee licensing evaluations, and develop and execute the disease area strategy.

Your Key Responsibilities:

• Responsible for clinical input to support Business Development & Licensing (BD&L) activities.
• Serve as the Clinical Development Representative to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP).
• Contribute to Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) designed for successful global regulatory approval/market access for one or more treatment indications and/or multiple programs.
• Drive creation and implementation of Clinical Development to support decision analysis and optimal resource allocation in program(s).
• Lead a cross-functional team through the creation of clinical components of key documents (e.g., Clinical Trial Protocols, Investigator’s Brochures, Clinical Study Reports, regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency.
• As the medical expert, lead interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs, Marketing, Health Economics & Outcomes Research), and internal decision boards.
• Together with Patient Safety, ensure continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance.
• Support registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s).
• Plan and implement publication and clinical communication strategy in coordination with Global Medical Affairs and Medical Writing, and provide input into key external presentations.

This position will be located at the East Hanover, New Jersey site and will not have the ability to be located remotely. This position will require 5% travel as defined by the business (domestic and/or international).

Minimum Requirements:

• MD, or Ph.D. degree with 10+ years’ experience in clinical research or drug development in an industry environment spanning clinical activities in Phases I-III/IV, including submission dossiers.
• A passion for Neuroscience.
• Advanced expertise in Neuroscience with the ability to innovate in clinical development study designs, provide relevant evidence to decision-makers, and interpret, discuss, and present clinical trial or section program level data.
• Detailed knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development processes.
• Demonstrated ability to establish strong scientific partnerships with key stakeholders.
• Demonstrated leadership and management skills with a documented track record of delivering high-quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry.

Desired Requirements:

• MD or equivalent, MD or MD/PhD in Neurology, Experience in Cell & Gene, Rare or Neuromuscular diseases, Neuroinflammation of interest.

Novartis Compensation and Benefit Summary:

The pay range for this position at commencement of employment is expected to be between: $261,100 and $484,900/year; however, while salary ranges are effective from 1/1/25 through 12/31/25, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, the employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Why Novartis:
Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us!

Accessibility and Reasonable Accommodations: The Novartis Group of Companies is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [e-mail] or call [phone] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion, or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.