Global Logistics Design & Cold Chain Lead

Alnylam Pharmaceuticals; Cambridge (MA); Hybrid; USD 122,000 - 165,000; Full time

Job summary

Alnylam Pharmaceuticals in Cambridge, MA, is seeking a Manager, Logistics Design & Cold Chain to lead the design and continuous improvement of global logistics standards, ensuring product integrity across the end-to-end supply chain.

You will translate requirements into scalable processes, define packaging and lane designs, collaborate with Quality, Validation, CMOs, and 3PLs, and drive risk mitigation, standards, and continuous improvement across cold chain operations.

Qualifications

• Bachelor's degree in Supply Chain, Logistics, Life Sciences, or a related discipline.
• Minimum 5 years of experience in logistics, cold chain, supply chain operations, packaging, transportation, or regulated distribution environments.
• Experience supporting temperature-controlled logistics, packaging qualification, lane assessments, or product integrity programs.
• Strong knowledge of GDP/GMP transportation requirements and regulated supply chain operations.
• Proven ability to work cross-functionally with Quality, Validation, Operations, and external partners.
• Strong communication skills with the ability to work cross-functionally and influence without direct authority.
• Ability to travel up to 20-25%, globally.

Responsibilities

• Support the development and maintenance of global packaging and transportation strategies across products, shipment types, and temperature profiles.
• Partner with Packaging Engineering, Validation, Quality, and Operations to define lane routing, carrier selection, pack-out requirements, and lane design inputs.
• Facilitate approval processes for packaging, validation and transportation configurations based on risk, performance and business needs.
• Identify and mitigate logistics risks (lane variability, disruptions, packaging performance) and define contingency strategies.
• Establish global standards for temperature control and environmental conditions across all shipment profiles.
• Ensure alignment between packaging, validation, transportation strategy, and product requirements to maintain product integrity.
• Facilitate the creation of logistics design policies, standards, and SOPs, and lead their implementation across assigned products, lanes, and logistics partners.
• Ensure compliance with GDP/GMP and regulatory requirements in partnership with Quality & Validation.
• Partner with internal teams and external providers to implement standardized logistics design practices across assigned products, lanes, or initiatives.
• Assess transportation and cold chain risks for assigned lanes, products, or logistics scenarios.
• Support the development of risk-based mitigation plans in partnership with Packaging Engineering, Validation, Quality, and Logistics Operations.
• Monitor lane and provider performance to identify potential product integrity or service reliability risks.
• Serve as a logistics design and cold chain point of contact for assigned projects, lanes, or operational initiatives.
• Collaborate with CMOs, 3PLs, logistics service providers, Quality, Validation, Manufacturing, Clinical Supply, Commercial Supply, and Trade Compliance.
• Support cross-functional decision-making related to transportation design, packaging configuration, lane setup, and shipment readiness.
• Identify opportunities to standardize and optimize logistics strategies across the global network.
• Drive improvements in service reliability, cost efficiency, and product protection.
• Analyze shipment performance, lane data, excursion trends, and carrier performance to recommend improvements.
• Evaluate and implement innovative technologies and solutions that enhance logistics performance and visibility.

Education

Bachelor's degree in Supply Chain, Logistics, Life Sciences, or a related discipline

Job description

Alnylam Pharmaceuticals in Cambridge, MA, is seeking a Manager, Logistics Design & Cold Chain to lead the design and continuous improvement of global logistics standards, ensuring product integrity across the end-to-end supply chain.

You will translate requirements into scalable processes, define packaging and lane designs, collaborate with Quality, Validation, CMOs, and 3PLs, and drive risk mitigation, standards, and continuous improvement across cold chain operations.