Global Kidney Commercial Strategy Lead (Hybrid)

Vertex Pharmaceuticals Incorporated; Boston (MA); Hybrid; USD 261,000 - 391,000; Full time

Job summary

Vertex Pharmaceuticals Incorporated is seeking an Executive Director, Global Commercial Strategy for the Kidney franchise to lead povetacicept strategy across IgAN and pMN. You will drive global launch planning, lifecycle management, and portfolio alignment, partnering with Development, Medical, Regulatory, Value & Access, and regional teams to optimize patient impact.

The role requires proven global commercial leadership, strong strategic planning, and the ability to build high-performing teams

Qualifications

• Extensive biopharmaceutical commercial experience in global strategy.
• Experience leading global launch strategy for specialty or rare diseases.
• Lifecycle management, forecasting, and evidence planning.
• Nephrology or complex markets launch experience preferred.
• Experience leading cross-functional teams in a matrixed environment.
• Strong strategic thinking and influencing skills.

Responsibilities

• Co-lead the povetacicept Kidney Program Team with the Development Lead, setting the integrated strategy across IgAN and pMN.
• Own the global commercial strategy for povetacicept in kidney, linking launch, lifecycle, evidence, and investment priorities.
• Lead GCS support for the U.S. IgAN launch and subsequent global launches, ensuring strategy and readiness.
• Own global lifecycle management for povetacicept in IgAN, expanding differentiation and value.
• Lead global commercialization and launch strategy for pMN, including market development and evidence needs.
• Shape development plans and commercial activities across IgAN and pMN, including forecasting and market research.
• Build deep understanding of IgAN and pMN markets, patient pathways, competition, and access dynamics.
• Ensure alignment between kidney strategy and broader povetacicept portfolio with other indications.
• Partner across Development, Medical, Regulatory, Value & Access, Finance, Manufacturing, and regional teams for a globally aligned plan.
• Communicate recommendations to senior leaders and governance bodies, outlining uncertainties and actions.
• Build and lead a high-performing kidney commercial team as the franchise grows.

Skills

Global strategy

Launch leadership

Lifecycle management

Cross-functional

Strategic thinking

Analytical rigor

Communication

Influencing

Education

Bachelor's degree

Advanced degree preferred

Job description

Vertex Pharmaceuticals Incorporated is seeking an Executive Director, Global Commercial Strategy for the Kidney franchise to lead povetacicept strategy across IgAN and pMN. You will drive global launch planning, lifecycle management, and portfolio alignment, partnering with Development, Medical, Regulatory, Value & Access, and regional teams to optimize patient impact.

The role requires proven global commercial leadership, strong strategic planning, and the ability to build high-performing teams