Global Head of In Vitro Pharmacology - Small Molecules

USA - 3316 Takeda Development Center Americas, Inc.; Cambridge (MA); Hybrid; USD 212,000 - 333,000; Full time

Benefits offered by this job

Executive compensation

Comprehensive benefits

Professional development

Job summary

Takeda in Cambridge, MA is seeking a Head of Small Molecule In Vitro Pharmacology to drive the scientific vision and build a global IVP organization. This senior leader will oversee discovery and early development interfaces, lead a geographically distributed team of scientists, and partner across ADME, DMPK and translational sciences to advance portfolio decisions.

You will shape strategy, set assay standards, implement scalable HTS pipelines, harness AI-enabled analytics, and represent Takeda

Qualifications

• PhD with 15+ years industry experience in discovery and early development.
• Proven executive leadership running global discovery pharmacology teams with global responsibilities, budgets, and strategic outcomes.
• Deep hands-on expertise in in vitro pharmacology including biochemical and cell-based assays, target engagement, orthogonal counter-screens, and quantitative dose response analysis.
• Experience with assay miniaturization, automation, informatics and HTS readiness.
• Exceptional communication and stakeholder management skills with ability to influence cross functional and executive audiences.
• Proven ability to hire, develop and retain senior scientific leaders.

Responsibilities

• Set global IVP strategy aligned with R&D priorities.
• Lead a distributed team of directors, managers and scientists.
• Define assay standards for design, validation, miniaturization and throughput.
• Establish scalable screening cascades for HTS and SAR profiling.
• Ensure translational readouts support hit-to-lead and IND decisions.
• Lead external representation and publications.
• Own budget and resource allocation for global IVP function.
• Drive adoption of new technologies and AI-leveraged capabilities.

Skills

In vitro pharmacology

Biochemical assays

Cell-based assays

Target engagement

Orthogonal counterscreens

Dose-response analysis

Assay miniaturization

Automation

Informatics

HTS readiness

Executive leadership

Stakeholder management

Education

PhD in Pharmacology/ Biochemistry/ Cell Biology

Tools

High content imaging

TR-FRET

SPR

BLI

Biophysical modalities

Job description

Takeda in Cambridge, MA is seeking a Head of Small Molecule In Vitro Pharmacology to drive the scientific vision and build a global IVP organization. This senior leader will oversee discovery and early development interfaces, lead a geographically distributed team of scientists, and partner across ADME, DMPK and translational sciences to advance portfolio decisions.

You will shape strategy, set assay standards, implement scalable HTS pipelines, harness AI-enabled analytics, and represent Takeda