Global Development Lead, Internal Medicine, Sr. Director (MD)

Scorpion Therapeutics; San Diego (CA); Hybrid; USD 275,000 - 458,000; Full time

Benefits offered by this job

Salary range 274,500–457,500 USD

Bonus target 25%

Long-term incentive

401(k) with matching

Paid vacation/holiday/personal days

Paid caregiver/ parental and medical  

Medical/prescription/dental/vision

Job summary

Scorpion Therapeutics seeks a senior clinical development leader to oversee Internal Medicine assets and obesity programs. You will head cross-functional teams across clinical, pharmacology, statistics, safety, and commercial, guiding study lifecycles from protocol design to submission.

The role requires extensive R&D experience, regulatory knowledge, and strong leadership to manage large teams and external partnerships, with a hybrid on-site work arrangement in San Diego.

Qualifications

• MD or DO required.
• 8+ years in clinical R&D (academia and/or biopharma).
• Experience in chronic weight management/endocrinology/internal medicine; Phase 1–3 clinical development and translational medicine.
• Extensive knowledge of global/regional regulation, ICH/GCP, adverse event management.
• Demonstrated medical/administrative/project management; able to manage/train large teams.

Responsibilities

• Serve as clinical point of accountability for assigned Internal Medicine assets; lead cross-functional Clinical Development Teams.
• Create and endorse the Clinical Development Plan and protocol design; partner throughout study lifecycle.
• Lead obesity portfolio clinical leadership (trial design, execution, reporting).
• Lead governance reviews; provide therapy area expertise (CRF design, signal interpretation, AE contextualization).
• Drive submission strategy and deliverables (IAP/IARP, submission TLFs; SCE/SCS; DSUR, PBRER; safety narrative plan; product label development/maintenance).
• Contribute to target product profiles; support product defense.
• Partner with external stakeholders (advisory boards, steering committees, DMC, adjudication committees, patients/advocates).
• Support trial-level statistical analysis plan, TLFs, database release; review IIR proposals.

Skills

Leadership in cross-functional teams

Clinical development leadership

Global regulatory knowledge

Communication skills

Education

MD/DO

Job description

Responsibilities

• Serve as clinical point of accountability for assigned Internal Medicine assets; lead cross-functional Clinical Development Teams (clinical, clinical pharmacology, statistics, safety, commercial, patient access, operations).
• Create and gain endorsement for the Clinical Development Plan and associated protocol design documents; partner throughout study lifecycle.
• Lead obesity portfolio clinical leadership as needed (trial design, execution, reporting).
• Lead governance reviews with trial clinicians; provide therapy area/indication expertise (CRF design, signal interpretation, adverse event contextualization).
• Drive submission strategy and deliverables (IAP/IARP, submission TLFs; SCE/SCS; DSUR, PBRER; safety narrative plan; product label development/maintenance).
• Contribute to target product profiles; support product defense.
• Partner with external stakeholders (e.g., advisory boards, steering committees, DMC, adjudication committees, patients/advocates).
• Support trial-level statistical analysis plan, TLFs, database release; review IIR proposals.

Basic Qualifications

• Education: MD or DO.
• Experience: chronic weight management/endocrinology/internal medicine; Phase 1–3 clinical development and translational medicine; 8+ years in clinical R&D (academia and/or biopharma).
• Extensive knowledge of global/regional regulation, ICH/GCP, adverse event management.
• Demonstrated medical/administrative/project management; effective verbal/written communication; manage/train large teams (designing/launching large teams preferred).

Competencies (required)

• Leadership, influence in matrix environments, accountability, conflict management, team building, and ability to deliver amid change.

Benefits/Compensation (as stated)

• Base salary range: $274,500–$457,500; bonus target 25%; eligibility for long-term incentive; 401(k) with matching and additional retirement contribution; paid vacation/holiday/personal days; paid caregiver/parental and medical leave; medical/prescription/dental/vision.

Work

• Up to 30% travel; hybrid role (on-site ~2.5 days/week).