Global Development Lead, Internal Medicine, Sr. Director (MD)

Scorpion Therapeutics; Pearl River (NY); Hybrid; USD 250,000 - 350,000; Full time

Benefits offered by this job

Pfizer Global Performance Plan bonus (

401(k) with matching

Paid vacation/holidays/personal days

Medical/dental/vision coverage

Job summary

Scorpion Therapeutics seeks a senior leader to drive clinical development in Internal Medicine, guiding study design, execution, and regulatory submissions worldwide. The role owns the Clinical Development Plan and protocol design, with pediatric plan development and milestone negotiation to ensure timely, budget-conscious delivery.

The incumbent provides therapy area expertise for data reviews, safety narratives, and product labeling support, while engaging external stakeholders and leading

Qualifications

• MD or DO with 8+ years in clinical research and development across Phase 1–3.
• Background in chronic weight management, endocrinology, or internal medicine.
• Extensive knowledge of global/regional regulation, ICH/GCP, and adverse event management.
• Demonstrated medical, administrative, and project management capabilities; effective communication.
• Experience leading/training large cross-functional teams; launching large teams preferred.

Responsibilities

• Lead cross-functional Clinical Development Team for Internal Medicine assets through study design, execution, and interpretation for worldwide regulatory submissions.
• Own and endorse the Clinical Development Plan and protocol design documents.
• Create pediatric investigation/study plan and protocol design documents for trial feasibility and execution.
• Negotiate milestones and ensure delivery of the clinical program within timelines and budget.
• Provide therapy area expertise for data review, safety narrative planning, and product labeling support.
• Develop submission-level deliverables and safety narratives; review safety plans.
• Engage external stakeholders to support clinical development strategy and program development.
• Provide regulatory submission support including DSUR, PBRER and product defense; ensure SOP compliance.

Education

MD or DO

Job description

Responsibilities:

• Lead cross-functional Clinical Development Team for assigned Internal Medicine asset(s) through study design, execution, and interpretation for worldwide regulatory submissions.
• Own and gain endorsement for the Clinical Development Plan and associated protocol design documents.
• Create pediatric investigation/study plan and protocol design documents to ensure trial feasibility and optimized execution.
• Negotiate tradeoffs, milestones, and ensure delivery of clinical program within agreed timelines and budget.
• Provide product/program input for target product profile(s).
• Drive innovative, bold clinical development decisions; develop clinical development enabling strategies (digital/innovation and patient engagement).
• Partner with trial clinicians on governance reviews (incl. Sci/Ops); provide category clinical development strategy input.
• Provide therapy area/indication expertise for clinical data review (CRF design, signal interpretation, adverse event contextualization).
• Provide specialized medical monitoring support if required.
• Contribute to trial-level statistical analysis plan, TLFs, table-listings-figures, and database release with statistics/programming.
• Develop submission-level deliverables (IAP, IARP, submission TLFs) including SCE and SCS; review/approve submission-level safety narrative plan.
• Support interpretation/communication of clinical trial data; support product label development and maintenance.
• Engage external stakeholders (Ad boards, Steering Committees, DMC, adjudication committees, patients/advocates) to support clinical development strategy and PDD development.
• Provide regulatory submission support (DSUR, PBRER) including product defense; ensure compliance with internal SOPs and external regulatory standards.
• Review IIR proposals.

Basic Qualifications:

• MD or DO.
• 8+ years of relevant experience in clinical research and development (academia and/or biopharma), with Phase 1–3 clinical development and translational medicine experience.
• Background in chronic weight management, endocrinology, or internal medicine.
• Extensive knowledge of global/regional regulation, ICH/GCP, and adverse event management.
• Demonstrated medical/clinical, administrative, and project management capabilities; effective verbal/written communication.
• Demonstrated experience managing/training large teams; designing/launching large teams preferred.

Additional Competencies/Skills:

• Ability to coordinate/execute clinical development or lifecycle strategy; influence cross-functional teams in a matrix.
• Leadership, influencing, conflict management, team building, accountability, and change agility.

Benefits:

• Participation in Pfizer Global Performance Plan (bonus target 25%) and eligibility for share-based long-term incentive.
• 401(k) with matching contributions and additional retirement savings contribution; paid vacation/holidays/personal days; paid caregiver/parental and medical leave; medical/prescription/dental/vision coverage.

Work/Environment:

• Up to 30% travel; hybrid role (on-site ~2.5 days/week).