Global Commercial Head, Immunology

AstraZeneca; Gaithersburg (MD); On-site; USD 268,000 - 402,000; Full time

Benefits offered by this job

Short-term incentive bonuses

Equity-based awards

Commissions for sales roles

Retirement programs

Paid time off

Health, dental, and vision coverage

Job summary

AstraZeneca in Gaithersburg, MD is seeking a Global Commercial Head, Immunology to lead the global business strategy and execution for a major Immunology asset. You will shape product strategy, maximize lifecycle value, and guide regional implementation with a senior cross‑functional team.

You will manage a high‑performing team, coordinate with Medical Affairs, Market Access, Regulatory, and Clinical Development, and ensure strong execution across markets.

Qualifications

• BA/BS in Business, Medical, Life Sciences or related field.
• US commercial and launch experience required.
• 10 years in pharmaceutical development and commercialization.
• Experience leading global brand strategy and execution.
• Strong cross-functional leadership and stakeholder management.

Responsibilities

• Develop and evolve the global commercial strategy, brand plan and operational priorities.
• Serve as the senior commercial voice on the global cross‑functional product team and shape key development, regulatory and lifecycle decisions.
• Partner with Medical Affairs, Market Access, Regulatory, Clinical Development, Insights & Analytics, Policy, Patient Advocacy, Finance, Supply and Commercial Excellence.
• Translate global strategy into clear direction for regions and markets, supporting effective execution, launches and lifecycle growth.
• Define positioning, priority audiences and the value proposition using market research and customer insight.
• Ensure forecasts and business plans are grounded in product strengths, unmet need and pricing considerations.
• Engage external experts, healthcare professionals and patient organizations to bring perspectives into strategy.
• Lead strategic agency and vendor relationships and ensure allocation of resources.
• Create an inclusive, high‑performing team environment and model AstraZeneca values.

Skills

Global brand leadership

US market experience

Launch experience

Forecasting

Market access

Pricing

Stakeholder influence

Digital capabilities

AI applications

Leadership

Education

BA/BS in Business, Medical, Life Sciences or related

MBA

Job description

At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. We are passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring innovative ideas to life. Respiratory & Immunology, part of AstraZeneca BioPharmaceuticals is a key disease area and growth driver to the Company.

Our ambition in Immunology is to transform care for people living with chronic, complex immune-mediated diseases. With a growing portfolio and pipeline, we are advancing innovative science and building the capabilities required to deliver meaningful, lasting impact for patients worldwide.

We have already made significant progress through the launch of our first medicine for systemic lupus erythematosus (SLE), and recently expanded through the launch of a subcutaneous formulation.

With further Phase 3 development programs currently ongoing in Cutaneous Lupus (CLE) and Lupus Nephritis (LN) we are excited to potentially reach additional specialties & patient groups. This is an opportunity to contribute to the continued evolution of an important Immunology franchise and help deliver both near‑term brand performance and long‑term value.

The Opportunity

We are seeking an experienced Global Commercial Head, Immunology to lead all aspects of the global business strategy and execution for a major Immunology asset. Reporting to the Vice President, Global Commercial Immunology, you will shape the product strategy, maximize its value across the lifecycle and ensure strong execution in regions and markets. You will lead a team of direct reports and serve as the senior commercial voice on the global product team and lead the global brand team.

What You’ll Do

• Develop and evolve the global commercial strategy, brand plan and operational priorities, grounded in patient, customer and market insights.
• Serve as the senior commercial voice on the global cross‑functional product team and shape key development, regulatory and lifecycle decisions.
• Partner with Medical Affairs, Market Access, Regulatory, Clinical Development, Insights & Analytics, Policy, Patient Advocacy, Finance, Supply and Commercial Excellence.
• Translate global strategy into clear direction for regions and markets, supporting effective execution, launches and lifecycle growth.
• Define positioning, priority audiences and the value proposition using robust market research, competitive intelligence and customer insight.
• Ensure forecasts and business plans are grounded in product strengths, unmet need, competitive dynamics, pricing and access considerations.
• Engage external experts, healthcare professionals, patient organizations and other stakeholders to bring patient and customer perspectives into strategy.
• Lead strategic agency and vendor relationships and ensure effective allocation of resources.
• Create an inclusive, high‑performing team environment; set a clear vision, coach and develop talent, and role‑model AstraZeneca values.

Size of Team

The Global Commercial Head will 3-5 direct reports and provide leadership across a broader global matrix.

Required Experience

• BA/BS in Business, Medical, Life Sciences or a related discipline.
• US commercial and launch experience.
• 10 years’ experience in pharmaceutical development and commercialization, including leadership of global brand strategy and execution.
• Strong expertise and a current understanding of the advanced treatment landscape, customers, competitors and evolving standards of care in rheumatology or dermatology.
• Demonstrated launch and lifecycle management success in a competitive specialty‑care environment, preferably at global and/or regional level.
• Experience using clinical evidence, market insights and competitive intelligence to shape commercial and development strategy.
• Strong understanding of forecasting, market research, insight generation, pricing and market access, and portfolio planning.
• Demonstrated success leading direct reports and cross‑functional teams in a complex global matrix.
• Ability to influence senior stakeholders across functions and geographies, communicate with clarity and make sound decisions in ambiguity.
• Experience leveraging digital capabilities and AI to strengthen commercial strategy and operational excellence.
• Scientific curiosity and a strong commitment to improving patient outcomes.

Desirable Experience

• Advanced degree, such as an MBA, MSc, MD or PhD.
• Established global and/or US relationships with key external experts in Immunology.

Why AstraZeneca?

This position is based at our Gaithersburg, MD campus. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life changing medicines. In‑person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and bold world.

AstraZeneca offers an environment where you can thrive by working with new drugs, digital approaches, and ever‑changing environments. Our pioneering value‑based agreements and Innovative Value Strategy solutions lead the way in the industry. We are driven by our determination to ensure the value of our medicines is realized. Our dynamic environment encourages creativity in designing strategies and innovative access solutions. We thrive on co‑creation and draw on diverse perspectives to overcome challenges. Join us to be part of a team that is passionate about making a meaningful impact on patient outcomes.

The annual base pay for this position ranges from $267,913 - 401,870 USD.

• short‑term incentive bonuses
• equity‑based awards for salaried roles
• commissions for sales roles

• qualified retirement programs
• paid time off (i.e., vacation, holiday, and leaves)
• health, dental, and vision coverage in accordance with the terms of the applicable plans

Date Posted

15-Oct-2026

Closing Date

29-Oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees.

In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics.

If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.