GI2 DMPK & Therapeutic Area Lead — Strategy & Impact

Takeda Pharmaceutical Co.; Cambridge (MA); On-site; USD 212,000 - 333,000; Full time

Job summary

Takeda Pharmaceutical Co. in Boston, MA seeks a GI2 Therapeutic Area Lead in DMPK&M to provide scientific leadership and strategic direction across discovery and development.

You will supervise DMPK&M project representatives and Modeling & Simulation scientists to meet global research goals and translate pipeline strategies into actionable plans. The role requires a PhD (or equivalent) with extensive DMPK&M expertise, strong leadership, and the ability to work across global teams

Qualifications

• PhD degree in a scientific discipline with 15+ years experience, MS with 21+ years experience, or BS with 23+ years experience including at least 9 years of Industry experience in pharmaceutical DMPK and modeling.
• Good understanding of the GI2 DDU/TAU project portfolio, disease indications, and typical DMPK&M considerations for patients.
• Deep drug discovery and development experience and profound DMPK&M expertise required.
• Experience in managing preclinical scientists and preparation of INDs, CTDs, NDAs, and MAAs.
• Proactive, innovative, with good problem-solving skills.
• Exceptional leadership, coaching, employee development skills.
• Ability to work strategically in a cross functional team and matrix environment.
• In-depth knowledge of the functional area, business strategies, and the company’s goals.
• Excellent written, presentation, and verbal communication skills.
• A track record of sustained, significant scientific contributions in DMPK and modeling, as demonstrated by publications and presentations.

Responsibilities

• Provides scientific leadership and strategic guidance on stage-appropriate questions related to DMPK&M to ensure the selection and development of clinical candidates with optimal drug development characteristics.
• Builds and enhances an external network to keep a pulse on scientific developments, novel strategies, partnership opportunities, and the latest competitive and regulatory landscape, particularly in relation to the GI2 therapeutic areas.
• Advises, reviews, and approves, on behalf of DMPK&M, milestone presentations and PRC narratives.
• Oversees and participates in regulatory activities, including the review and approval of robust and fit-for-purpose submission packages in the GI2 therapeutic area.

Skills

Strategic leadership

DMPK & modeling

Regulatory understanding

Cross-functional leadership

Communication

Team management

Education

PhD in scientific discipline

MS with 21+ years experience

BS with 23+ years experience

Job description

Takeda Pharmaceutical Co. in Boston, MA seeks a GI2 Therapeutic Area Lead in DMPK&M to provide scientific leadership and strategic direction across discovery and development.

You will supervise DMPK&M project representatives and Modeling & Simulation scientists to meet global research goals and translate pipeline strategies into actionable plans. The role requires a PhD (or equivalent) with extensive DMPK&M expertise, strong leadership, and the ability to work across global teams