Genomics & Diagnostics Research Associate II

Sarmal Inc

San Diego (CA)

On-site

USD 72,000 - 85,000

Full time

14 days+

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Benefits offered by this job

Medical, dental, and vision insurance
Company-paid life insurance
401(k) retirement plan
Generous paid time off
Voluntary benefits and employee perks

Job summary

Sarmal, Inc., a San Diego biotechnology company, seeks a Research Associate II to support development and optimization of molecular diagnostic assays for our pathogen-detection platform. You will execute surface-based nucleic acid detection assays, prepare reagents, perform fluorescence- and CE-based experiments, analyze data, and help transition validated methods into standardized procedures.

The ideal candidate is organized, detail-oriented, and enjoys hands-on lab work in a fast-paced startup

Qualifications

  • Hands-on laboratory experience with molecular biology or biochemical assays.
  • Experience with nucleic acid hybridization assays, fluorescence-based detection methods, enzymatic reactions, or surface-based capture assays.
  • Experience preparing master mixes, serial dilutions, reagent stocks, and low-volume liquid handling.
  • Familiarity with fluorescence plate readers, capillary electrophoresis, or similar analytical instrumentation.
  • Ability to analyze experimental data using Excel; experience with JMP or similar software is a plus.
  • Strong troubleshooting skills, attention to detail, and ability to maintain high-quality experimental documentation.
  • Ability to independently execute experiments while effectively collaborating within a multidisciplinary team.
  • Experience with automated liquid handling systems (Hamilton, Tecan, Beckman, Opentrons, or similar) is a plus.
  • Experience in regulated diagnostics/biotech/medical devices is desirable.

Responsibilities

  • Execute surface-based nucleic acid detection assays using 96- and 384-well formats.
  • Prepare master mixes, serial dilutions, oligonucleotides, and enzyme reagents.
  • Perform fluorescence plate-based assays and capillary electrophoresis sample prep.
  • Analyze data, summarize results, and present findings to the Assay Development team.
  • Assist in optimizing assay performance through troubleshooting and evaluation.
  • Maintain accurate lab notebooks and SOP documentation.
  • Support reagent inventory and routine lab operations.
  • Contribute to verification, reproducibility studies, and technology transfer.

Skills

Molecular biology
Biochemical assays
Nucleic acid assays
Excel data analysis
Troubleshooting
Team collaboration

Education

B.S./M.S. in molecular biology or related field
Industry experience: 2–4 years (B.S.) or 1–2 years (M.S.)
Hands-on assay development in industrial/translational setting
Experience with nucleic acid hybridization or fluorescence-based assays
Assay optimization and troubleshooting experience

Tools

Fluorescence plate readers
Capillary electrophoresis
Automated liquid handling
JMP

Job description

Sarmal, Inc., a San Diego biotechnology company, seeks a Research Associate II to support development and optimization of molecular diagnostic assays for our pathogen-detection platform. You will execute surface-based nucleic acid detection assays, prepare reagents, perform fluorescence- and CE-based experiments, analyze data, and help transition validated methods into standardized procedures.

The ideal candidate is organized, detail-oriented, and enjoys hands-on lab work in a fast-paced startup

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