General Partner - East Coast

Careers Signant Health; United States; On-site; USD 350,000 - 550,000; Full time

Job summary

Signant Health is seeking a General Partner, Commercial to lead a defined portfolio of strategic Big Pharma and CRO accounts. This executive will drive growth, client value, and long-term partnerships, aligning client objectives with Signant Health’s strategic priorities and ensuring profitable outcomes.

The role demands deep industry expertise, stellar relationship management, and a track record of closing complex commercial agreements that enhance margins and growth across multiple geographies.

Qualifications

• 15+ years in senior client-facing leadership roles in tech, pharma services or life sciences.
• Proven track record managing $50MM+ accounts with double-digit revenue growth.
• Deep domain knowledge of Big Pharma and CROs and their R&D, commercial and regulatory landscapes.
• Strong executive presence to engage with C-suite and senior stakeholders.
• Expertise closing complex commercial agreements that drive revenue and margins.
• Experience leading strategic account governance and executive reporting.

Responsibilities

• Own and develop the commercial strategy for an assigned portfolio of pharma and CRO accounts.
• Serve as the primary executive relationship owner with C-suite stakeholders.
• Lead governance, portfolio analysis, ROI modelling and long-term opportunity mapping.
• Identify and manage delivery risks with internal teams to protect client trust and margins.
• Protect and optimise account profitability with informed commercial trade-offs.
• Monitor client dynamics and stakeholder influence to anticipate risks and opportunities.
• Chair cross-functional governance forums aligning client expectations with internal teams.
• Represent Signant Health at executive client engagements to reinforce market leadership.
• Identify and pursue new strategic opportunities within the portfolio.

Skills

Senior leadership

Key account management

C-suite engagement

Revenue growth

Governance frameworks

Cross-functional collaboration

Strategic sales

Opportunity mapping

Education

MBA

Tools

CRM platforms

Job description

ABOUT SIGNANT HEALTH

At Signant Health, we help bring life-changing treatments to patients faster. We are a global evidence generation company that supports clinical trials with smart technology, scientific expertise, and hands-on operational support — so better data leads to better decisions in healthcare. We embrace AI and advanced technologies to enhance every aspect of what we do, from data analysis to operational efficiency.

Our teams work at the intersection of science, technology, and patient experience, delivering digital solutions powered by AI innovation that make clinical trials more efficient, more accurate, and more accessible around the world. Trusted by leading pharmaceutical companies and CROs, our platforms and services support studies across more than 90 countries and have contributed to hundreds of new drug approvals.

If you are motivated by meaningful work, global impact, and innovation in clinical research and digital health — including the opportunity to work with cutting-edge AI technologies — you will find purpose and opportunity at Signant Health.

ABOUT THE ROLE

The General Partner, Commercial is the senior executive owner of a defined portfolio of strategic Big Pharma and CRO accounts, responsible for driving transformative growth and long-term partnership value. This role operates as the primary commercial and relationship leader for accounts generating $50MM–$100MM+ in revenue, ensuring that client engagements deliver measurable outcomes aligned to both client objectives and Signant Health's strategic priorities. The General Partner balances commercial growth, operational delivery, and stakeholder influence to position Signant Health as an indispensable, forward-looking partner — achieving net bookings targets, revenue goals, and margin expectations.

KEY ACCOUNTABILITIES

1. Own and develop the commercial strategy across an assigned portfolio of strategic pharma and CRO accounts, driving consistent year-on-year revenue growth through expansion, cross-sell, and renewals.
2. Serve as the primary executive relationship owner, building and sustaining trusted partnerships with C-suite stakeholders, department heads, procurement, and key influencers across client organisations.
3. Lead account governance and strategic planning, including portfolio analysis, ROI modelling, and long-term opportunity mapping that aligns client priorities with Signant Health's solutions.
4. Proactively identify and manage delivery risks, working closely with internal operational teams to resolve challenges before they impact client trust or margin performance.
5. Protect and optimise account profitability, making informed commercial decisions and trade-offs that maintain healthy margins while supporting sustainable growth.
6. Map and monitor client organizational dynamics, identifying shifts in stakeholder influence, priorities, and competitive positioning to stay ahead of risks and opportunities.
7. Chair cross-functional governance forums and steering committees, ensuring alignment between client expectations and internal Commercial, Project Management, and Technical Delivery teams.
8. Represent Signant Health at senior industry forums and executive client engagements, reinforcing the organization's profile and thought leadership within the Life Sciences and pharma tech space.
9. Identify and pursue new strategic opportunities within the existing portfolio, leveraging deep client knowledge and industry relationships to expand scope and deepen partnership value.

KNOWLEDGE, SKILLS & ATTRIBUTES

Essential:

1. 15+ years in senior client-facing leadership roles, including 7+ years at a senior level within technology, software companies, or pharma services serving the Life Sciences sector.
2. Proven track record managing $50MM+ accounts in SaaS, tech services, or pharma-adjacent environments, with consistent double-digit revenue growth in competitive, multi-stakeholder settings.
3. Deep domain knowledge of Big Pharma and CROs, including R&D, commercial, and regulatory landscapes.
4. Strong executive presence with the ability to engage, influence, and build consensus across C-suite and senior stakeholder groups.
5. Demonstrated ability to structure and close complex commercial agreements that drive sustained revenue growth and margin performance.
6. Experience leading account governance frameworks, including strategic account planning, performance metrics, and executive reporting.
7. Collaborative, cross-functional working style with the ability to align diverse internal teams around shared client outcomes.
8. Proven ability to identify and manage organisational risk proactively, translating challenges into opportunities that strengthen client relationships.

Desirable:

1. MBA or equivalent advanced degree.
2. Familiarity with clinical trial technology, eCOA, eConsent, or related Life Sciences solutions.
3. Relevant certifications in strategic account management or pharma tech.
4. Experience working across matrix organisations in multiple geographies.
5. Advanced knowledge of enterprise CRM platforms and strategic account planning methodologies.

WHY SIGNANT HEALTH?

At Signant Health, your work has real impact. Everything we build, support, and deliver helps advance clinical research and bring new treatments to patients faster — improving lives around the world. Our teams combine science, technology, and operational expertise to solve complex clinical trial challenges, and every role contributes to that mission.

We offer a collaborative, global environment where you can grow your career while working alongside experts across clinical, technology, data, and operations, with opportunities to learn, take ownership, and drive meaningful innovation — not just maintain the status quo.

If you are looking for purpose-driven work, smart colleagues, and the opportunity to help shape the future of clinical research and digital health, Signant Health is the place to do it.

At Signant Health, accepting difference isn't enough — we celebrate it, we support it, and we nurture it for the benefit of our team members, our clients, and our community. We are proud to be an equal opportunity workplace and an affirmative action employer, committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or veteran status. Prior to their start date, all new hires are required to be verified through a thorough background check and identity verification to confirm eligibility for employment.