Fullstack Software Engineer (Senior / Staff)

Genesis Therapeutics; California (MO); On-site; Full time

Benefits offered by this job

Competitive salary and equity

Medical, dental, and vision insurance

401(k) program

Collaborative learning environment

Job summary

A pioneering software company in molecular AI is seeking a full-time engineer to own and evolve the platform for computational chemists. This involves building tools for visualizing molecules and scaling data infrastructure. Candidates should be experienced in software development, comfortable with the entire tech stack, and passionate about drug discovery. The role offers a hybrid work model, competitive salary, equity, and comprehensive benefits including medical insurance and a 401(k).

Qualifications

• Deep thinker with attention to detail and architectural thinking.
• Experience in shipping production code and managing projects end-to-end.
• Enthusiasm for software engineering in drug discovery.

Responsibilities

• Own and evolve the full-stack platform for computational chemists.
• Build tools for visualizing molecules and analyzing ML models.
• Scale data infrastructure for deep learning and molecular dynamics.

Skills

Frontend interfaces

Backend services

Data pipelines

Molecular property prediction

Machine learning

Job description

Location

San Mateo, CA; New York, NY

Employment Type

Full time

Location Type

Hybrid

Department

AI

Genesis Molecular AI is building a world‑class software team to solve problems in drug discovery through machine learning, biophysical simulation, and computational chemistry. We are looking for engineers excited to help develop new medicines and play a critical role in building out our software platform.

You will

• Own and evolve the full‑stack platform that computational chemists use daily, from data exploration and experiment management to real‑time visualization, shipping AI‑native workflows and modern interaction patterns that shorten the loop between hypothesis and insight

• Build and expand tools for visualizing molecules and proteins, analyzing ML models, and managing complex chemical workflows

• Partner with machine learning engineers and computational chemists to develop and productionize new computational methods for molecular property prediction

• Scale our data infrastructure to handle billions of datapoints and thousands of parallel deep learning and molecular dynamics jobs

You are

• A deep thinker who reasons from first principles, balances attention to detail with architectural thinking, and has an investigative curiosity to find the root cause of a problem

• Comfortable owning problems across the entire stack — frontend interfaces, backend services, data pipelines, and infrastructure

• Experienced shipping production code and driving projects end‑to‑end with minimal hand‑holding

• Excited to work at the intersection of software engineering, drug discovery, and machine learning

What we offer

• The opportunity to work on high impact tools and products that are immediately deployed to accelerate the discovery of new medicines

• Strong technical coworkers in AI, software, and chemistry, who all have a powerful mix of intellectual curiosity and humility. The team reads and discusses 1‑2 machine learning or chemistry papers every week to stay on top of the field and inspire new ideas

• Competitive salary and equity. Medical, dental, and vision insurance, and a 401(k) program

About Genesis Molecular AI

Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company’s generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry‑leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science‑focused investors, signed multiple AI‑focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high‑impact targets.

Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.