Software Engineer - Core Infrastructure

Genesis Molecular AI; San Mateo (CA); On-site; USD 120,000 - 160,000; Full time

Benefits offered by this job

Competitive salary

Equity

Medical, dental, and vision insurance

401(k) program

Job summary

Genesis Molecular AI is seeking an Infrastructure Engineer in San Mateo, CA, to develop and maintain multi-cloud compute infrastructure. The role involves supporting ML model training and ongoing drug discovery efforts. Ideal candidates have over 5 years of experience in cloud infrastructure, proficient in Python and Kubernetes, and a passion for advancing drug design through AI. The company offers a competitive salary, equity, and comprehensive benefits including medical, dental, and a 401(k) program.

Qualifications

• 5+ years of experience building and maintaining cloud infrastructure at scale.
• Proficient with Python, Bash, Terraform, Ray, and Kubernetes.
• Experience with compute clusters running distributed ML training jobs.

Responsibilities

• Maintain and grow multi-cloud compute infrastructure.
• Build out monitoring, resource allocation, and deployment automation.
• Work on orchestration scheduling framework for compute optimization.

Skills

Cloud infrastructure management

Python

Bash

Terraform

Ray

Kubernetes

Job description

Genesis Therapeutics is building a world-class computational team to solve problems in drug discovery through machine learning, biophysical simulation, and computational chemistry. We are looking for an Infrastructure Engineer that is excited to help develop new medicines and play a critical role in building out our AI platform.

You Will

• Work on our infrastructure team to maintain and grow our multi‑cloud compute infrastructure that supports our ML model training, computational chemistry research, and ongoing drug discovery efforts
• Build out our configuration and procedures for monitoring, resource allocation, and deployment automation, as we continue to grow our autoscaling compute clusters to handle larger workloads
• Work on orchestration scheduling framework to increase our execution throughput, reliability, and compute utilization across heterogeneous pipelines

You Are

• 5+ years of experience building and maintaining cloud infrastructure at scale, e.g. within AWS or GCP
• Proficient with Python, Bash, Terraform, Ray and Kubernetes
• Ideally, experience building and maintaining compute clusters running distributed ML training jobs with 1,000+ GPUs
• Nice to have: hands‑on experience with physical hardware + datacenter management

What We Offer

• The opportunity to work on high impact infrastructure that is used to accelerate the discovery of new medicines
• A world‑class, tight‑knit team of good‑hearted people across software, machine learning, computational chemistry, medicinal chemistry, and biology
• Competitive salary and equity. Medical, dental, and vision insurance, and a 401(k) program

About Genesis Molecular AI

Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company’s generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry‑leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science‑focused investors, signed multiple AI‑focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high‑impact targets.

Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.