Frontline Bioprocess Engineer - Downstream Ops

Lonza; Vacaville (CA); Hybrid; Confidential; Full time

Benefits offered by this job

Performance-related bonus

Medical, dental and vision insurance

401(k) matching plan

Life insurance, as well as short-term/

Disability insurance

Employee assistance programs

Paid Time Off

Job summary

Lonza in Vacaville, CA is seeking a Frontline Engineer to support biopharmaceutical manufacturing. You will act as a system and equipment SME, addressing complex technical challenges and driving continuous improvement in a GMP environment.

This site-based role emphasizes real-time collaboration, startup and qualification of new equipment, data-driven improvements, and cross-functional partnership across Manufacturing, Quality, Engineering, Maintenance, MSAT, and EHS.

Qualifications

• Bachelor’s degree in Chemical Engineering or a related field.
• Experience in supporting pharmaceutical/biotech manufacturing equipment in a GMP environment.
• Hands-on experience in downstream biopharmaceutical manufacturing operations (chromatography, viral filtration, etc.).
• Demonstrated project leadership delivering improvements and system changes.
• Excellent communication and collaboration across functions.
• Proficiency with SAP, MS Office, P&IDs, and data visualization tools.

Responsibilities

• Support 24/7 manufacturing operations as a system and equipment SME, ensuring readiness.
• Investigate unplanned events using root cause analysis to deliver sustainable solutions.
• Lead small to medium improvement projects driving operational excellence.
• Partner cross-functionally with Manufacturing, QA, Engineering, Maintenance, MSAT, Automation, EHS.
• Provide SME support for startup, commissioning, and qualification of new equipment.
• Analyze equipment and process data to identify trends and improvements.
• Support CAPEX projects and New Product Transfers from concept to qualification.

Skills

System SME

Cross-functional collaboration

Project leadership

Data analysis

Communication skills

Education

Bachelor's degree in Chemical Engineering

Tools

SAP

MS Office

P&IDs

Data visualization tools

Job description

Lonza in Vacaville, CA is seeking a Frontline Engineer to support biopharmaceutical manufacturing. You will act as a system and equipment SME, addressing complex technical challenges and driving continuous improvement in a GMP environment.

This site-based role emphasizes real-time collaboration, startup and qualification of new equipment, data-driven improvements, and cross-functional partnership across Manufacturing, Quality, Engineering, Maintenance, MSAT, and EHS.