Executive Medical Director (Retina Program)

Scorpion Therapeutics; United States; On-site; USD 250,000 - 360,000; Full time

Job summary

Scorpion Therapeutics seeks an Executive Medical Director to oversee Phase 1 ophthalmology trials focused on retinal diseases, including wet age-related macular degeneration and diabetic macular edema. You will lead study design, safety oversight, and first-in-human clinical readouts.

Reporting to the CMO with a dotted line to the SVP of Research & Early-Stage Product Development, you will manage cross-functional teams, develop biomarker strategies, and drive regulatory submissions and external

Qualifications

• MD with ophthalmology residency and retina subspecialty.
• 10+ years of clinical ophthalmology research in biopharma.
• Expertise in Phase 1 trials, gene therapy, and regulatory submissions.
• Knowledge of ICH-GCP and FDA guidelines.
• Excellent communication skills.

Responsibilities

• Leading study design
• Safety oversight
• Data analysis and clinical readouts
• Managing cross-functional teams (clinical operations, biometrics, regulatory, CMC)
• Developing biomarker strategies
• Authoring regulatory documents
• Engaging with external stakeholders

Skills

Phase 1 trials expertise

Regulatory submissions experience

ICH-GCP FDA guidelines knowledge

Excellent communication skills

Education

MD

Ophthalmology residency with retina subspecialty

Job description

Role

Executive Medical Director overseeing Phase 1 ophthalmology clinical trials, primarily for retinal diseases such as wet age-related macular degeneration and diabetic macular edema.

Responsibilities

• Leading study design


• Safety oversight


• Data analysis and clinical readouts


• Managing cross-functional teams (clinical operations, biometrics, regulatory, CMC)


• Developing biomarker strategies


• Authoring regulatory documents


• Engaging with external stakeholders

Qualifications

• Medical degree (MD), ideally with ophthalmology residency and retina subspecialty


• 10+ years of clinical ophthalmology research experience in biopharma


• Expertise in Phase 1 trials, gene therapy, and regulatory submissions


• Knowledge of ICH-GCP and FDA guidelines


• Excellent communication skills

High-value

Focus on ophthalmology, gene therapy, early-phase clinical development, biomarker integration, and regulatory interactions.

Collaboration / Reporting

Reports to CMO, dotted line to SVP Research & Early-Stage Product Development.

Work Setup

Travel up to 20%; physical activity includes sedentary work typical of office settings.