Executive Director, Oncology Clinical Development

Rigel Pharmaceuticals Inc.; South San Francisco (CA); Hybrid; USD 285,000 - 335,000; Full time

Job summary

Rigel Pharmaceuticals, Inc. in South San Francisco seeks an Executive Director, Clinical Development to lead the clinical and medical work for hematology and oncology programs, from study design through data interpretation and reporting.

This role partners with the Vice President, Clinical Development to translate strategies into plans, manage budgets, and oversee medical leadership to ensure scientific rigor across trials.

Qualifications

• MD or equivalent medical degree required.
• Board certification in hematology or oncology preferred.
• Typically 8+ years in clinical research or drug development with 5+ years in regulatory or development leadership is expected.

Responsibilities

• Develop clinical development plans for assets, define patient population, endpoints, and evidence; recommend options to VP.
• Lead protocol and amendment development with cross-functional input.
• Serve as medical lead/monitor for trials; address investigator questions and ensure consistent decisions across sites.
• Review safety and efficacy data; identify concerns and recommend study actions.
• Guide medical review of study data and support database readiness and interpretation of results.
• Partner with Clinical Operations and CROs to resolve issues affecting patient care and timelines; contribute to risk mitigation.
• Lead or review Investigator's Brochures, study reports, and submission documents; ensure conclusions reflect evidence.
• Support health authority interactions and present analyses at meetings as delegated by VP.
• Build relationships with investigators and experts; support investigator meetings and advisory discussions.
• Present program findings to internal teams; escalate safety issues and proposed changes to strategy to VP.
• Contribute to publications and scientific presentations; mentor clinical staff.

Skills

Leadership

Clinical development

Regulatory submissions

Mentoring

Team management

Education

MD or equivalent medical degree

Board certification in hematology/oncology preferred

Job description

Rigel Pharmaceuticals, Inc. in South San Francisco seeks an Executive Director, Clinical Development to lead the clinical and medical work for hematology and oncology programs, from study design through data interpretation and reporting.

This role partners with the Vice President, Clinical Development to translate strategies into plans, manage budgets, and oversee medical leadership to ensure scientific rigor across trials.