Executive Director, Global Product Lead, Immunology Research and Development

AstraZeneca; Cambridge (MA); On-site; USD 251,610 - 377,415; Full time

Benefits offered by this job

401(k) plan

Paid vacation and holidays

Health benefits including medical, dental, and vision

Job summary

AstraZeneca in Cambridge, MA is seeking a Global Product Lead for early stage immunology programs. The role requires crafting asset strategies and leading cross-functional teams to deliver on clinical milestones.

The ideal candidate has a master's degree or higher, over 10 years of experience in pharma, and a proven ability to manage high-risk projects. A competitive salary range of USD 251,610.40 – 377,415.60 is offered, alongside comprehensive benefits.

Qualifications

• 10+ years of experience in the pharmaceutical industry.
• Ability to travel nationally and internationally.
• Proven skills managing and controlling large budgets.

Responsibilities

• Craft asset strategy to achieve clinical milestones.
• Define Life Cycle Management investment options.
• Execute clinical trials within timelines and budget.
• Lead performance with cross-functional teams.

Skills

Pharma proven experience

Early stage drug development

Influencing executive stakeholders

Budget management

Problem solving

Education

Masters, Ph.D., or MD

Job description

About AstraZeneca

AstraZeneca is a global, science‑led, patient‑focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. We are one of the world’s leading pharmaceutical companies.

Immunology Research and Development (iRED)

At AstraZeneca iRED, we do immunology differently. We develop life‑changing medicines by combining deep patient insight with cutting‑edge modalities, focusing on the most challenging diseases and underserved populations, to accelerate our path to be a top immunology company in the industry. It’s our big vision that unites and inspires us. In iRED, our portfolio of immunology programs includes clinical stage and pre‑clinical candidates across rheumatology, dermatology, gastroenterology, and other indications. AstraZeneca iRED is a place built on courage, curiosity, and collaboration – we make bold decisions driven by patient outcomes.

What You’ll Do

The Global Product Lead (GPL) will be accountable for the asset strategy of multiple early stage immunology programs. The GPL will provide strategic leadership to the cross‑functional Global Product Team to execute and deliver the pre‑clinical and clinical development plan, aligned to the Life Cycle Management plan developed by the GPT. At AstraZeneca, the GPL holds an exceptionally critical and exciting role, with impact across the organization and visibility to executive management.

Responsibilities

• Craft the overall asset strategy that will enable achievement of early stage clinical milestones, progressive discharge of technical and regulatory risk, and ultimately a differentiated and value‑generating profile at time of approval.
• Define the range of Life Cycle Management investment options and recommend investment decisions to improve the value of the product to the business.
• Develop and progress the product Target Product Profile (TPP).
• Define and craft the product business case and development plan that would deliver the profile defined in the TPP.
• Execute clinical trials to governance‑agreed timelines and budget, while working with the team and functional management as required to resolve issues.
• Shape the molecule’s integrated strategic science story through the product lifecycle.
• Persuasively deliver recommendations and proposals to executive management.
• Ensure role‑modeling for internal partners and KEE engagement in strategy development and scientific exchange.
• Ensure effective and transparent risk, opportunity and issue management at strategic, tactical and operational levels.
• Lead performance with cross‑functional team. Build and effectively lead robust cross‑functional teams.

Essential Skills / Experience

• Masters, Ph.D., or MD with 10+ years of pharma proven experience.
• Experience in early stage drug development and knowledge of all stages of the drug development process, coupled with regulatory and commercial insights.
• Performance/results driven mindset with a proven track record of delivering high‑risk projects in a complex environment.
• Ability to influence both executive level internal and globally renowned external stakeholders.
• Ability to set program level vision and motivate / inspire GPT and functional teams.
• Comfort with assessing multiple (sometimes conflicting) arguments and ability to frame clear messages to simplify decision making.
• Fully conversant with basic and translational science to inform product differentiation and strategy.
• Ability to interpret and communicate technical information into business language.
• Adaptive problem solving and learning and ability to navigate complex organizations and system.
• Proven skills and experience of managing and controlling large budgets.
• Ability to travel nationally and internationally.
• Entrepreneurial mindset and proven ability to learn new information rapidly and effectively.

Desirable Skills / Experience

• Specific and relevant immunology development expertise.
• Experience in AstraZeneca’s other multiple therapeutic areas (oncology, cardiovascular / renal / metabolic, rare disease, respiratory).
• Late stage clinical development or commercial experience.

The annual base salary for this position ranges from USD 251,610.40 – 377,415.60. Base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience. In addition, our positions offer a short‑term incentive bonus opportunity; eligibility to participate in our equity‑based long‑term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered include a qualified retirement program (401(k) plan); paid vacation and holidays; paid leaves; and health benefits, including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, the employee will be in an “at‑will” position and the company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, company or individual department/team performance, and market factors.

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.