Executive Clinical Scientist — Immunology & Biologics

AiLux S.r.l.; United States; Remote; USD 180,000 - 270,000; Full time

Job summary

Ailux is seeking a Clinical Scientist at ED/Sr Dir/Director level to bridge laboratory discoveries with clinical applications in autoimmune and inflammatory diseases. You will lead trials from Phase 0 to PoC, integrate translational and biomarker strategies, and partner with Regulatory, Clinical Operations, and external partners to ensure milestones are met.

You will supervise cross-functional teams, mentor colleagues, and contribute to governance discussions while advancing Ailux's pipeline

Qualifications

• Advanced degree in immunology, autoimmunity, inflammation, or allergy.
• 3–5+ years of clinical R&D in pharma/biotech/CROs with trials experience.
• Data review and safety signal detection in trials.
• Broad understanding of FDA/EMA/ICH-GCP regulatory standards.
• Strong cross-functional leadership, data synthesis, and communication.
• Experience in experimental medicine or PoC-to-late-stage development.
• Multi-region trial experience (US, China, Europe).
• Experience with biologics, multispecifics, or cell therapies.

Responsibilities

• Clinical Strategy: design and oversight of trials (Phase 0–Phase 2a PoC), ensure PoM/PoC alignment.
• Translational Science: translate preclinical PK/PD data into starting doses and patient selection.
• Regulatory filings: prepare clinical sections for IND/CTA submissions and safety updates.
• Stakeholder management: coordinate sites, CROs, and external partners; present data at governance meetings.
• Team leadership: matrix leadership, mentorship, and capability building.

Skills

Immunology

Clinical trials

Leadership

Regulatory

Mentorship

Strategic planning

Education

PhD/MD/MS/PharmD

Job description

Ailux is seeking a Clinical Scientist at ED/Sr Dir/Director level to bridge laboratory discoveries with clinical applications in autoimmune and inflammatory diseases. You will lead trials from Phase 0 to PoC, integrate translational and biomarker strategies, and partner with Regulatory, Clinical Operations, and external partners to ensure milestones are met.

You will supervise cross-functional teams, mentor colleagues, and contribute to governance discussions while advancing Ailux's pipeline