Exec Dir Enterprise Architect

Regeneron Pharmaceuticals, Inc (USA); Village of Sleepy Hollow (NY); On-site; USD 286,000 - 476,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc. seeks an Executive Director to lead Enterprise Architecture, shaping the technology vision, standards, and governance that align business strategy with scalable, secure platforms.

The role partners with senior IT and business leadership to drive architecture across data, cloud, and integration domains, balancing strategic thinking with hands-on depth. This on-site role is based at Sleepy Hollow, NY or Warren, NJ, four days per week.

Qualifications

• Bachelor's degree in a related field required.
• Master's degree or MBA strongly preferred.
• 17+ years in enterprise architecture, IT strategy, or leadership roles.
• Experience leading architecture in a global, matrixed organization.

Responsibilities

• Define and own the enterprise architecture strategy and roadmaps.
• Lead governance, standards, and reference architectures across domains.
• Partner with Security, Risk, and Compliance to meet regulatory obligations.
• Translate business strategy into technology plans and investments.
• Mentor and grow a high-performing architecture team.

Skills

TOGAF

Zachman

Cloud platforms

Enterprise integration

AI platforms

Security architecture

DevOps / CI/CD

Regulatory/compliance

Education

Bachelor's degree

Master's degree or MBA

Job description

This role leads Enterprise Architecture for the organization, setting the technology vision, standards, and governance that align business strategy with scalable, secure, and future-ready technology platforms. The Executive Director partners with senior IT and business leadership to shape the enterprise technology roadmap, drive architecture decision‑making across data, cloud and infrastructure, application, and integration domains, and ensure technology investments deliver measurable business value. This is both a strategic and hands‑on leadership role, requiring the ability to influence at the executive level while maintaining the technical depth to guide complex, enterprise‑wide architecture decisions, and to build and mentor a high‑performing architecture organization. Security and AI architecture are delivered through close collaboration with the CISO and CAIO organizations, which maintain their own dedicated architecture teams; business architecture is owned by a separate business strategy function outside Digital and Technology.

Where and When

This is an on‑site position 4 days/week, primarily based at our Sleepy Hollow, NY or Warren, NJ office. If eligible, we can offer relocation benefits; we cannot offer a fully remote option.

Enterprise Architecture Strategy & Vision

Define and own the enterprise architecture strategy, principles, and target‑state blueprints across the data, cloud and infrastructure, application, and integration domains, incorporating security and AI architecture standards set in partnership with the CISO and CAIO organizations. Translate business strategy and digital transformation priorities into a coherent, multi‑year enterprise technology roadmap. Establish and evolve the enterprise's architecture operating model, ensuring architecture decisions scale with business growth and complexity. Assess emerging technology trends (AI/ML, cloud‑native platforms, automation) and determine their strategic fit and adoption path for the enterprise. Champion a “business capability first” architecture approach, ensuring technology investments map directly to business outcomes.

Architecture Governance & Standards

Establish and lead the enterprise architecture governance framework, including review boards, design authority processes, and exception management. Define and enforce enterprise architecture standards, patterns, and reference architectures across build, buy, and integrate decisions. Own the architecture review process for major programs and capital investments, ensuring alignment with enterprise standards, security, and regulatory requirements. Maintain the enterprise architecture repository (current‑state and future‑state models, technology inventories, and roadmaps) as an authoritative source of truth. Partner with Security, Risk, and Compliance to ensure architecture decisions meet enterprise risk tolerance and regulatory obligations (e.g., GxP, data privacy).

Technology Roadmap & Investment Planning

Lead enterprise‑wide technology rationalization efforts, identifying opportunities to consolidate, retire, or modernize legacy platforms. Partner with Finance and business unit leaders to build the business case for architecture‑driven investments, balancing innovation with cost discipline. Guide platform and vendor selection decisions for enterprise‑critical systems, ensuring architectural fit, scalability, and total cost of ownership are fully evaluated. Own the enterprise's cloud and infrastructure strategy, ensuring architecture decisions support performance, resilience, and cost efficiency at scale. Drive the integration architecture strategy across the enterprise, enabling seamless data flow and interoperability between core business systems.

Business & Digital Transformation Partnership

Serve as a trusted architecture advisor to business unit leaders, translating business problems into technology‑enabled solutions. Partner with product, engineering, and program leadership to embed architecture thinking early in the delivery lifecycle, reducing rework and technical debt. Lead architecture input into major digital transformation and modernization initiatives, ensuring solutions are designed for scale, security, and long‑term maintainability. Evaluate and guide the adoption of AI, automation, and data platforms to accelerate business capabilities and competitive differentiation. Act as an escalation point for cross‑functional architecture conflicts, driving resolution through data‑driven, business‑aligned decision‑making.

Solution & Platform Architecture Oversight

Provide senior oversight and quality assurance for solution architectures developed by domain and solution architects across the enterprise. Ensure architectural consistency and reuse across programs, preventing siloed or duplicative technology investments. Guide the design of resilient, secure, and scalable platform architectures for enterprise applications, data platforms, and integration layers. Champion architecture practices that support DevOps, CI/CD, and infrastructure‑as‑code adoption across delivery teams. Oversee technical due diligence for mergers, acquisitions, and strategic partnerships, assessing architectural risk and integration complexity.

Executive Stakeholder Engagement & Communication

Present enterprise architecture strategy, roadmaps, and investment recommendations to executive leadership, technology governance forums, as needed. Build strong, trusted relationships with the Digital and Technology Leadership, and business unit executives to ensure architecture remains a strategic partner, not a bottleneck. Communicate complex technical concepts and trade‑offs in clear, business‑relevant terms to non‑technical executive audiences. Represent the enterprise architecture function in vendor, industry, and partner forums, staying current on best practices and market direction. Establish and sustain the operating model for collaboration with the CISO and CAIO organizations' own architecture teams — defining clear decision rights, escalation paths, and shared standards so security and AI architecture decisions remain aligned to enterprise architecture without duplicated ownership. Partner with the business strategy function that owns business architecture, ensuring enterprise technology roadmaps remain traceable to business capability models maintained outside Digital and Technology.

People Leadership, Mentoring & Team Culture

Build, lead, and develop a high‑performing architecture team, directly leading the Data & AI, Cloud & Infrastructure, Application, and Integration Domain Architects, and fostering a culture of technical excellence and collaboration. Mentor and coach architects and senior technical leaders, investing in career growth, technical depth, and succession planning. Establish architecture communities of practice and knowledge‑sharing forums that elevate architecture maturity across the broader technology organization. Champion diversity, equity, and inclusion in hiring, development, and team culture within the architecture function. Model and reinforce a culture of intellectual curiosity, pragmatism, and accountability across the architecture team.

Technical Competencies

• Deep expertise in enterprise architecture frameworks and methodologies (TOGAF, Zachman, or equivalent) and their practical application in a large, complex organization.
• Strong technical grounding across cloud platforms (AWS, Azure, GCP), enterprise integration, data architecture, and application architecture patterns.
• Strong grounding in enterprise integration architecture — API management, event‑driven patterns, and integration platform strategy.
• Working knowledge of AI/ML platforms, data and analytics architecture, and emerging technology evaluation.
• Experience with enterprise security architecture, identity and access management, and regulatory/compliance frameworks relevant to the industry (e.g., GxP, data privacy).
• Familiarity with modern software delivery practices — DevOps, CI/CD, microservices, and infrastructure‑as‑code.

Leadership & People Skills

• Proven ability to build, scale, and lead high‑performing architecture teams, including hiring, developing, and retaining top technical talent.
• Experience leading architecture functions within a global, matrixed organization, including geographically distributed teams.
• Ability to mentor and grow architects and technical leaders, building bench strength and succession depth.
• Experience establishing and sustaining a collaborative operating model with peer architecture functions (e.g., the CISO's and CAIO's own architecture teams), ensuring clear accountability without duplicated ownership.

Strategic & Business Skills

• Strong business acumen and the ability to translate business strategy into a coherent, executable technology roadmap.
• Sound judgment in balancing innovation, risk, cost, and speed to market in architecture decision‑making.
• Ability to lead through ambiguity, structuring clear technology direction from complex or evolving business requirements.

Communication & Stakeholder Abilities

• Executive presence and the ability to influence and communicate effectively with senior business and technology leaders, including at the EVP and possibly the board level.
• Ability to translate complex technical topics into clear, business‑relevant narratives for non‑technical audiences.
• Strong collaboration skills across global, cross‑functional, and cross‑cultural stakeholder groups.

Requirements

• Bachelor’s degree in Computer Science, Information Technology, Engineering, or a related field is required.
• A Master’s degree or MBA is strongly preferred.
• 17+ years of progressive experience in enterprise architecture, IT strategy, or technology leadership roles.
• 10+ years in senior leadership roles guiding architecture, engineering, or technology strategy teams within a large, complex, global organization.

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

We are committed to building a workplace with an inclusive culture.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Salary Range (annually) $285,600.00 - $475,900.00

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.