Evolutionary Protein Platform Scientist

Arcadiascience; Emeryville (CA); On-site; USD 130,000 - 190,000; Full time

Benefits offered by this job

Competitive compensation

Equal opportunity workplace

Job summary

Arcadia Science in Emeryville, CA, seeks a Platform Scientist to develop computational approaches for studying natural protein variation across macroevolutionary timescales. You will integrate sequence, structure, and function to inform tool development, validation, and open science contributions.

The role emphasizes cross‑disciplinary collaboration, open‑science publication, and a strong foundation in molecular evolution and biochemistry/biophysics.

Qualifications

• PhD in evolutionary biology or related field.
• At least one year of post‑PhD full‑time experience.
• Expertise in developing and applying computational approaches to study protein evolution using sequences, structures, and functional data.
• Familiarity with data analysis using Python or R.
• Excellent verbal and written science communication for diverse audiences.

Responsibilities

• Produce and analyze computational workflows to interrogate and integrate protein information across non‑model clades.
• Apply phylogenetic comparative methods, ancestral sequence reconstruction, or selection inference to large phylogenomic protein datasets across non‑model lineages.
• Use comparative analyses of natural protein variation to inform Arcadia's organism and target selection capabilities.
• Troubleshoot computational challenges independently and creatively.
• Collaborate with cross‑disciplinary teams to validate computational tools, contribute to shared research goals, and accelerate broader scientific efforts.
• Synthesize ideas, data, and findings into fully open‑access pubs and engage with the scientific community to maximize impact and garner feedback.

Skills

Computational biology

Phylogenetic methods

Strong communication

Collaborative teamwork

Education

PhD or equivalent in evolutionary biology, molecular biology, computational biology, or related field

Post‑PhD research experience (1+ year)

Tools

Python

R

Job description

Arcadia Science in Emeryville, CA, seeks a Platform Scientist to develop computational approaches for studying natural protein variation across macroevolutionary timescales. You will integrate sequence, structure, and function to inform tool development, validation, and open science contributions.

The role emphasizes cross‑disciplinary collaboration, open‑science publication, and a strong foundation in molecular evolution and biochemistry/biophysics.