Equipment Operations Engineer II

Veracyte, Inc.; South San Francisco (CA); On-site; USD 90,000 - 120,000; Full time

Job summary

Veracyte, Inc. is seeking an Equipment Operations Engineer II for our South San Francisco headquarters. You will support reliability, compliance, and operational availability of clinical and research lab equipment across our lifecycle program.

You will coordinate IQ/OQ/PQ, calibrations, preventive maintenance, and decommissioning; manage service vendors; and work with cross-functional teams to sustain regulatory standards and continuous improvement.

Qualifications

• BS/BA in Engineering or equivalent work experience.
• Hands-on equipment engineering or reliability background in regulated env.
• Experience writing equipment qualification plans and calibration strategies.
• Familiarity with lab instrumentation and maintenance standards.

Responsibilities

• Support equipment lifecycle processes from procurement to decommissioning.
• Coordinate IQ/OQ/PQ, calibration, and preventive maintenance activities.
• Manage internal investigations and service coordination for equipment issues.
• Collaborate with R&D, QA, and Clinical Operations to minimize disruption.
• Maintain compliant documentation and support audits and inspections.
• Develop maintenance strategies to improve reliability and reduce downtime.

Skills

Equipment engineering

Reliability engineering

Calibration

Root cause analysis

Documentation

Cross-functional

Regulatory compliance

Analytical thinking

Problem solving

Time management

Education

Bachelor's degree in Engineering

Tools

Microsoft Office

Google Suite

CMMS familiarity

LIMS integration

Job description

At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte enables our employees to not only make a meaningful impact on the lives of patients, but to also learn and grow within a purpose driven environment. This is what we call the Veracyte way - it's about how we work together, guided by our values, to give clinicians the insights they need to help patients make life-changing decisions.

Our Values:

• We Seek A Better Way : We pursue bold ideas, embrace complexity, and keep pushing forward.
• We Make It Happen : We act with urgency, deliver with excellence, and always find a way.
• We Are Stronger Together : We engage with empathy, align around what's best for Veracyte, and celebrate as one team.
• We Care Deeply : We show up with integrity, kindness, and respect for one another.

The Position:

Veracyte is seeking a highly motivated, experienced, and detail-oriented Equipment Operations Engineer II to join our Equipment Engineering and Operations team at our South San Francisco headquarters.

The Equipment Operations Engineer II supports reliability, compliance, and operational availability of laboratory equipment across clinical and research environments in adherence to Veracyte's equipment lifecycle management program. The scope of equipment includes a diverse range of assets such as liquid handlers, spectrophotometers, analyzers, and more.

The ideal candidate will bring a collaborative spirit and work cross-functionally with teams in Automation, Product Development, Quality, and Clinical Operations. Under general guidance, the Equipment Operations Engineer II applies technical knowledge to resolve routine issues, maintain equipment records, and contribute to continuous improvement initiatives that support reliable laboratory operations.

This is a full-time, non-exempt, onsite role, with a schedule of Tuesday - Saturday, 9am - 5pm.

Responsibilities:

• Support optimization and adherence to the equipment lifecycle program and processes from procurement, installation, qualification (IQ/OQ/PQ), calibration, and preventive maintenance to decommissioning.
• Independently manage equipment systems, including internal investigations and service coordination, documentation, and continuous improvement related to equipment performance. Troubleshoot and support root cause investigations for equipment failures and implement correct actions.
• Support cross-functional efforts related to new equipment onboarding, equipment relocations, obsolescence planning, and lab expansions.
• Coordinate maintenance, calibration, verification, and qualification activities across internal stakeholders (R&D and CLIA) and external service vendors to minimize impact on lab workflows while ensuring regulatory compliance.
• Maintain accurate and compliant documentation for all equipment-related activities, support audits, inspections, and internal reviews.
• Support development of equipment maintenance strategies to minimize downtime and increase overall equipment reliability.
• Support investigations as SME in NCR's and CAPA's as needed.
• Support development and authoring equipment specifications, user requirements, and IQ/OQ protocols. Support equipment qualification activities.
• Ensure all equipment and processes meet quality and regulatory standards (CLIA, CAP, IVD, and/or FDA regulations).
• Adhere to procedures and policies outlined within Veracyte's quality management system.

Who You Are:

Required Qualifications

• A minimum of 3 years of related experience with a BS/BA or higher degree in an Engineering field or equivalent work experience.
• A minimum of 3 years of hands-on experience in equipment engineering or reliability engineering within a highly regulated environment.
• A minimum of 2 years of experience developing/writing equipment qualification plans, calibration strategies, and maintenance & operation procedures.
• Familiarity with lab instrumentation, preventive maintenance, and calibration standards.
• Effective analytical and problem-solving skills with the ability to diagnose complex equipment issues and drive resolution independently or collaboratively.
• Proficient with common software tools (e.g. Microsoft Office, Google Suite).
• Strong organizational skills with a keen attention to detail and documentation accuracy.
• Effective communication and interpersonal skills; ability to work cross-functionally.
• Excellent time management skills to support a fast-paced working environment.

Preferred Qualifications

• Experience with sequencing assays and automation platforms.
• Familiarity with CMMS (BMRAM, Limble, EAM, SAP) and LIMS integration.
• Working knowledge of root cause analysis tools (e.g. 5 whys, fishbone, FMEA) and reliability principles.
• Experience with Six Sigma principals, SSGB or other reliability certification a significant plus.

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