Epidemiology Forecasting Director

Vertex Pharmaceuticals LLC; Boston, Northern (MA, KY); Hybrid; USD 192,000 - 288,000; Full time

Job summary

Vertex Pharmaceuticals LLC is seeking a Director of Epidemiology Forecasting in Boston to oversee strategic plans for estimating disease incidence, prevalence, and population size globally. You will ensure scientifically rigorous estimates across development stages and partner with clinical, regulatory, and commercial teams to inform planning and communications.

The role demands a PhD/DrPH in Epidemiology with extensive industry experience, exceptional written and oral communication, and a

Qualifications

• PhD/DrPH in Epidemiology with 10+ years in biopharma/consulting.
• Experience developing disease population size estimates and systematic reviews.
• Ability to lead cross-functional teams and translate data to insights.

Responsibilities

• Lead literature reviews and observational studies to produce rigorous disease estimates.
• Generate global incidence, prevalence, and population size estimates for disease areas.
• Collaborate with commercial, medical, regulatory, and other functions.
• Support cross-functional planning and align on investment at each development stage.
• Develop innovative epidemiologic solutions when evidence is sparse.

Skills

Epidemiology leadership

Cross-functional collaboration

Scientific writing

Oral communication

Data interpretation

Stakeholder management

Strategic planning

Education

PhD/DrPH in Epidemiology

MPH/MSc with 12+ years' experience

Job description

Job Description The Epidemiology Forecasting team develops patient population forecasts used to inform commercial opportunity and forecasting, clinical trial planning, long-range planning, regulatory filings, and external communications. The Director, Epidemiology Forecasting is responsible for supporting programs through the execution of strategic plans to obtain scientifically rigorous global estimates of the incidence, prevalence, and population size for diseases being investigated for treatment. The role will report to the Senior Director, Epidemiology Forecasting.

Key Responsibilities:

• Lead systematic literature reviews and database/disease registry studies and contribute to primary observational studies to ensure the development of scientifically rigorous estimates of disease incidence, prevalence, and population size
• Generate quality global estimates of disease incidence, prevalence, and population size for disease areas
• Collaborate with cross-functional partners in commercial, business development, medical, clinical, regulatory, corporate communications, and other functions
• Support internal processes and participate in cross-functional teams to achieve alignment of strategic plans and recommended approach/level of investment at each stage of development to ensure quality epi deliverables meet the needs of the organization
• Develop innovative solutions to ensure the organization has the relevant epidemiologic information, particularly where existing evidence is sparse

Key Requirements:

• PhD/DSc/DrPH in Epidemiology or related discipline with at least 10 years of industry experience in the biopharmaceutical or consulting environment or MPH/MSc with at least 12 years' experience
• Directly relevant experience in:
  • Developing disease population size estimates
  • Executing research to generate scientifically rigorous epidemiology estimates, including systematic literature reviews and primary observational studies
  • Supporting population sizing activities across research, business development, and long-range planning
• Ability to thrive in a fast-paced matrixed environment and navigate multiple competing priorities
• Exceptional written and oral communication skills with a keen ability to translate complex data into digestible information
• Flexible, "outside the box" thinker who embodies a collaborative approach that embraces diverse perspectives
• Culturally sensitive collaborator able to effectively lead cross-functional teams to drive alignment with business and stakeholder needs while managing timelines and budgets

Pay Range:

$192,200 - $288,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]

Help Us Achieve Our Mission

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases - cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia - and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune's 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.