Epidemiology Forecasting, Associate Director

Vertex Pharmaceuticals LLC; Boston (MA); Hybrid; USD 172,000 - 258,000; Full time

Benefits offered by this job

Remote-Eligible

Annual bonus

Equity awards

Total rewards benefits

Job summary

Vertex Pharmaceuticals LLC in Boston seeks an Associate Director to lead epidemiology forecasting within HEOR. You will generate global disease incidence, prevalence and population size estimates to inform development, commercial planning, and regulatory filings, collaborating with clinical, regulatory and commercial partners.

The role offers flexibility to be in-person, hybrid, or remote, with a focus on rigorous methods, systematic literature reviews, and real-world data analyses.

Qualifications

• PhD/DrPH in Epidemiology or related field with 8+ years in biopharma/consulting
• MPH/ MSc in Epidemiology with 10+ years experience also acceptable
• Experience developing disease population size estimates and conducting systematic literature reviews

Responsibilities

• Lead literature reviews and registry studies to develop incidence and prevalence estimates
• Generate global disease incidence, prevalence and population size estimates
• Collaborate with commercial, clinical, regulatory, and communications teams
• Support cross-functional planning and investment decisions across development stages
• Develop innovative epidemiologic solutions when evidence is sparse

Skills

Epidemiology forecasting

Cross-functional collaboration

Scientific communication

Real-world data analysis

Leadership in matrixed teams

Education

PhD/DrPH in Epidemiology

MPH/MSc in Epidemiology

Job description

Epidemiology Forecasting, Associate Director### Epidemiology Forecasting, Associate DirectorApply: Boston, MA: Full time: Posted Today: End Date: November 13, 2026 (6 days left to apply): REQ-30570**Job Description****Job Summary:** Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society. The Associate Director role is within HEOR’s Epidemiology Center of Excellence (CoE), a specialized team that develops patient population forecasts used to inform commercial opportunity and forecasting, clinical trial planning, long-range planning, regulatory filings, and external communications.In this role, the Associate Director will be responsible for supporting drug development programs in Vertex’s pipeline through the execution of strategic plans to obtain scientifically rigorous global estimates of the incidence, prevalence, and population size for diseases being investigated for treatment. The Associate Director will serve as a strategic partner to colleagues throughout the organization, providing technical epidemiology expertise on projects. The role will report to the Senior Director, Epidemiology Center of Excellence.The role has flexibility to be in-person, hybrid, or remote.**Key Responsibilities:*** Lead systematic literature reviews and database/disease registry studies and contribute to primary observational studies to ensure the development of scientifically rigorous estimates of disease incidence, prevalence, and population size* Generate quality global estimates of disease incidence, prevalence, and population size for disease areas being investigated for treatment with Vertex’s product candidates* Collaborate with cross-functional partners in commercial, business development, medical, clinical, regulatory, corporate communications, and other functions* Support internal processes and participate in cross-functional teams to achieve alignment of strategic plans and recommended approach/level of investment at each stage of development to ensure quality epidemiology deliverables meet the needs of the organization* Develop innovative solutions to ensure the organization has the relevant epidemiologic information, particularly where existing evidence is sparse**Qualifications:*** PhD/DSc/DrPH in Epidemiology or related discipline with at least 8 years of industry experience in the biopharmaceutical or consulting environment or MPH/MSc with at least 10 years’ experience* Directly relevant experience in: + Developing disease population size estimates + Executing research to generate scientifically rigorous epidemiology estimates, including systematic literature reviews and primary observational studies + Supporting population sizing activities across research, business development, and long-range planning* Ability to thrive in a fast-paced matrixed environment and navigate multiple competing priorities* Exceptional written and oral communication skills with a keen ability to translate complex data into digestible information* Demonstrated experience applying claims-based analytic methods in epidemiologic research, including disease prevalence estimation, using real-world data sources* Flexible, “outside the box” thinker who embodies a collaborative approach that embraces diverse perspectives* Culturally sensitive collaborator able to effectively lead cross-functional teams to drive alignment with business and stakeholder needs while managing timelines and budgets* Experience in rare diseases a plus At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.**Pay Range:**$172,000 - $258,000**Disclosure Statement:**The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Flex Designation:**Remote-Eligible**Flex Eligibility Status:**In this Remote-Eligible role, you can choose to be designated as: 1. **Remote**: work remotely five days per week and come into the office on occasion – you’re always welcome on-site; **or select** 2. **Hybrid**: work remotely up to two days per week; **or select** 3. **On-Site**: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.#LI-Remote**Company Information**Vertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]