Enterprise AI Enablement Director

Vertex Pharmaceuticals LLC; Boston, Northern (MA, KY); Hybrid; USD 186,000 - 280,000; Full time

Benefits offered by this job

Hybrid work option

Annual bonus eligibility

Equity awards

Flexible work arrangements

Job summary

Vertex Pharmaceuticals LLC seeks a Director of Enterprise AI Enablement to drive AI adoption across the organization, partnering with Workforce Strategy, Learning, Governance, and Communications. You will shape change strategies, develop practical AI-enabled experiences, and coach leaders to lead responsible, compliant AI use, delivering measurable value for Vertex and patients.

You will manage an integrated enablement roadmap, work with cross-functional teams to remove adoption barriers, and

Qualifications

• Bachelor’s degree in related field or equivalent experience.
• Advanced degree preferred, especially I/O or organizational behavior.
• 10+ years in enterprise change management, learning strategies, or tech adoption.

Responsibilities

• Lead enterprise AI enablement roadmap with clear milestones.
• Shape a unified experience across teams for AI adoption.
• Oversee change management readiness, reinforcement plans, and adoption metrics.
• Develop AI capabilities and role-specific experiences with Learning and Governance teams.
• Coach leaders and managers to drive responsible, compliant AI use.
• Build an AI champion network to accelerate adoption.
• Create reusable frameworks and standards for change, learning, and adoption.
• Define measurement of fluency and adoption to inform improvements.

Skills

Change management

AI fluency

Learning strategy

Stakeholder management

Communication

Facilitation

Adult learning

Education

Bachelor's degree

Advanced degree preferred

Tools

AI platforms

Job description

Job Description

At Vertex, we continue to invest in a future-ready workforce where AI helps people strengthen expertise, improve decision-making and create greater impact for our people and patients. We are looking for a Director, Enterprise AI Enablement to amplify the value AI creates across Vertex. Reporting to the Executive Director, Workforce Strategy & Innovation, you will lead the change management and enablement strategy to help employees, managers, and leaders consistently use AI with confidence, clarity, and accountability. Partnering across Workforce Strategy & Innovation, Learning, Internal Communications, Data Technology & Engineering, governance teams - and with leadership you will translate Vertex’s AI strategy into a clear, connected employee experience. This includes practical guidance, learning, manager support, and adoption plans and campaigns that help teams use our tools responsibly, apply AI where it improves work, and build new habits that create measurable value. To succeed, you will stay close to the AI frontier, applying curiosity and sound judgment to identify new capabilities and help teams adopt AI in ways that are effective, compliant, and create measurable value for Vertex and patients. You will model responsible use by continuously learning, applying AI to innovate your own work, and championing practices that create value.

Key Duties & Responsibilities

• Enterprise AI enablement roadmap.
• Shape and drive an integrated roadmap that builds AI fluency, leads change, and accelerates adoption across Vertex, with clear priorities, milestones, and measures of success.
• Integrated employee experience. Partner with the teams building, securing, governing, communicating, teaching, and deploying AI solutions to create a clear, connected employee experience.
• Change management. Lead the change approach for AI-enabled ways of working, including readiness assessments, employee and manager preparation, adoption barriers, and reinforcement plans that help new habits stick.
• Workforce AI fluency. Define the AI capabilities employees, managers, and leaders need, then partner with Learning and other teams to deliver practical, role-relevant experiences that build confidence through application.
• Leader and manager enablement. Equip leaders and managers to coach their teams on effective, responsible, and compliant use, create space for learning and experimentation, and help their teams apply AI to improve their experience and redesign their work.
• AI adoption network. Build and activate a network of AI champions and change partners to share relevant examples, support colleagues, and strengthen adoption within their functions.
• Tools and standards. Create reusable frameworks, resources, and standards that help teams deliver consistent change, learning, and adoption across AI initiatives.
• Adoption measurement and improvement. Define how progress, fluency, behavior change, and adoption will be measured, provide leaders with a clear view of what is working, and use employee feedback and data to continually improve the approach.

Knowledge and Skills

• Deep knowledge of enterprise change management, behavior change, organizational effectiveness, and technology adoption.
• Strong understanding of adult learning and capability building, including how to translate enterprise needs into practical, role-relevant experiences.
• Ability to connect communications, learning, leader and manager enablement, change management, and employee feedback into a coherent enablement approach.
• Ability to translate AI strategy and redesigned work into clear expectations, guidance, support, and reinforcement for employees, managers, and leaders.
• Ability to define meaningful measures of fluency, adoption, behavior change, and sustainment and use evidence to improve the approach.
• Practical fluency with AI tools and emerging AI capabilities, and sound judgment about responsible and compliant use, with the credibility to model the behaviors the role is helping build.
• Strong facilitation, communication, and stakeholder-partnership skills across functions and levels of seniority.
• Ability to influence and align stakeholders across a complex organization without relying on direct authority.

Education and Experience

• Bachelor’s degree in organizational development, organizational behavior, human resources, psychology, education, communications, or a related field – or relevant experience.
• Advanced degree preferred.
• A graduate degree in industrial/organizational psychology or organizational behavior is especially relevant to this role.
• Typically requires 10 or more years of experience in enterprise change management, organizational effectiveness, capability building, learning strategy, culture transformation, or technology adoption, or the equivalent combination of education and experience.
• Demonstrated experience leading change and adoption for a large-scale, enterprise-wide transformation in a complex, matrixed organization.
• Experience developing and scaling practical capability-building or learning approaches for employees, managers, and leaders.
• Experience coordinating change, communications, learning, and adoption across multiple functions and stakeholder groups.
• Experience defining measures of adoption, capability, behavior change, or sustained use and applying the findings to improve an enterprise approach.

Pay Range

$186,400 - $279,600

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status

In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail].

Vertex's diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives.

For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram.

Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.