Engineer – Synthetic Molecule Design and Development (SMDD)

Initial Therapeutics, Inc.; Indianapolis (IN); On-site; USD 64,000 - 168,000; Full time

Job summary

An established industry player is seeking creative and energetic candidates for a role in synthetic drug development. This exciting opportunity involves collaborating with a dynamic team of chemists and engineers to facilitate unit operation development and process optimization. You will contribute to the creation of life-changing medicines by applying engineering principles to design and scale up processes for clinical trials and regulatory submissions. If you are passionate about making a difference in healthcare and thrive in a collaborative environment, this position is perfect for you.

Benefits

company bonus

401(k) plan

pension

vacation benefits

medical benefits

dental benefits

vision benefits

life insurance

fitness benefits

employee clubs and activities

Qualifications

• Bachelor's or Master's degree in Chemical Engineering or related field required.
• 0-12 years industry experience for B.S. and 0-9 years for M.S.

Responsibilities

• Generate process design knowledge for small molecules and peptides.
• Engage in creative solutions for process improvement.
• Design and execute laboratory experiments effectively.

Skills

synthetic organic chemistry

problem-solving

verbal communication

written communication

collaboration

prioritization

Education

B.S. in Chemical Engineering

M.S. in Chemical Engineering

Tools

numerical engineering modeling tools

Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Synthetic Molecule Design and Development (SMDD) is involved in key activities for the development of synthetic active pharmaceutical ingredients from pre-clinical phases through commercialization of drug substances and drug products. Our scientists and engineers develop key technical and business solutions across the portfolio using their deep technical expertise to accelerate testing of the clinical hypothesis and overall drug development. SMDD delivers on these responsibilities by recognizing diverse talent and cultures are necessary to bring the next generation of life-changing medicines to patients.

Our team is looking for creative and energetic candidates to facilitate unit operation development and process optimization of synthetic drug candidates to support clinical trials, regulatory submission, and product commercialization. The position presents an opportunity to work on dynamic teams comprised of process chemists, analytical chemists, formulation scientists, and engineers.

Position Responsibilities

• Generate process design and unit operation knowledge based on engineering principles for small molecules, peptides, oligonucleotides, and other emerging therapeutic modalities.
• Ensure successful scale-up of processes through fundamental engineering principles and equipment knowledge.
• Design and execute laboratory experiments.
• Develop drug substance or drug product processes and manufacturing technologies.
• Engage in generating creative solutions for improving existing processes and the creation of novel ones.
• Transfer process technical information to internal and external manufacturing sites. Provide technical oversight to external collaboration partners for laboratory and manufacturing activities.
• Author and maintain documentation such as laboratory notebooks and technical reports.
• Apply fundamental engineering and business principles to design and characterize synthetic processes. Use numerical engineering modeling tools to characterize reaction kinetics, reaction mechanisms, and process separations.
• Design effective and efficient process and equipment flow strategies, ensuring equipment is selected which is suitable and appropriate for its intended use, given the specific needs of the process.
• Stay informed about new technology and best practices. Propose, justify, evaluate, and implement new equipment, processing techniques, and technologies.
• Utilize technology to improve safety, quality, and productivity, both in development and manufacturing.
• Publish and share original research externally through peer-reviewed articles and conferences.

Minimum Qualifications:

• B.S (0-12 years industry experience) or M.S. (0-9 years industry experience) in chemical engineering or closely related field.

Additional Skills/Preferences

• Strong technical skills in synthetic organic chemistry with experience as a hands-on technical contributor in a laboratory environment.
• Demonstrated problem-solving skills.
• Strong verbal and written communication skills and ability to collaborate in a team environment.
• Ability to prioritize multiple activities and handle ambiguity.

Additional Information

• Travel: 0 to 10%.
• Location: Indianapolis, IN; Lilly Technology Center – North (LTC-N)

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $64,500 - $167,200.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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