Electron Microscopy Specialist

Uncover; Hamilton (MT); On-site; USD 70,000 - 80,000; Full time

Benefits offered by this job

Medical + Vision coverage for employee

Paid time off & holidays

401K match up to 5%

Educational benefits

Employee referral bonus

FSA

Parking reimbursement

DCAP

Transportation reimbursement

Job summary

Axle is seeking an experienced Electron Microscopy Specialist to support infectious disease research at NIAID’s Rocky Mountain Laboratories in Hamilton, Montana. The role combines hands-on EM work with collaboration across multiple research groups to generate high-quality imaging data.

You will perform sample prep, immuno-EM experiments, and operate TEM/SEM instruments while helping expand capabilities such as CLEM, FIB-SEM, and cryo-EM.

Qualifications

• Degree in a relevant field (Cell Biology, Structural Biology, Biophysics, or similar).
• At least 5 years of relevant job experience in biological electron microscopy.
• Solid understanding of EM sample preparation and imaging workflows.
• Strong experience with immuno-electron microscopy.
• Experience operating and troubleshooting EM instruments.
• Excellent communication and collaboration across projects.

Responsibilities

• Prepare biological samples for electron microscopy and perform imaging and analysis.
• Design and conduct immuno-electron microscopy (immuno-EM) experiments.
• Operate and help maintain TEM and/or SEM instruments, including troubleshooting.
• Collaborate with NIAID investigators to plan experiments and interpret results.
• Help bring new capabilities online (CLEM, FIB-SEM, cryo-EM).
• Maintain organized records per NIH standards for rigor and reproducibility.
• Train and support lab members in EM techniques.
• Contribute to lab operations and safety compliance.

Skills

Immuno-electron microscopy

EM sample preparation

EM imaging workflows

Instrument troubleshooting

Team collaboration

Documentation & NIH standards

Education

Degree in Cell Biology/Structural Biology/Biophysics

Tools

TEM

SEM

Image analysis tools

Job description

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits We Offer:

• 100% Medical, Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts: Healthcare (FSA)
• Parking Reimbursement Account (PRK)
• Dependent Care Assistant Program (DCAP)
• Transportation Reimbursement Account (TRN)

About the Role

Axle is looking for an experienced Electron Microscopy Specialist to join our team supporting research at NIAID’s Rocky Mountain Laboratories in Hamilton, Montana . In this role, you’ll work closely with scientists in a collaborative, fast-paced environment, helping generate high-quality imaging data that supports infectious disease research.

This is a hands‑on position for someone who enjoys both the technical side of electron microscopy and the collaborative nature of working with different research groups. If you have strong immuno-EM experience and are excited about learning and applying newer approaches like CLEM, FIB-SEM, and cryo-EM, this could be a great fit.

What You’ll Do

• Prepare biological samples for electron microscopy (fixation, embedding, sectioning, staining) and perform imaging and analysis.
• Design and conduct immuno-electron microscopy (immuno-EM) experiments.
• Operate and help maintain TEM and/or SEM instruments, including troubleshooting when needed.
• Work closely with NIAID investigators to plan experiments, interpret results, and solve technical challenges.
• Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM.
• Keep clear, well‑organized records in line with NIH standards for rigor and reproducibility.
• Train and support other lab members or facility users in EM techniques.
• Contribute to the overall operation of the lab, including equipment upkeep and safety compliance.

What We’re Looking For

• Degree in a relevant field (Cell Biology, Structural Biology, Biophysics, or similar).
• At least 5 years of relevant job experience in biological electron microscopy.
• Solid understanding of EM sample preparation and imaging workflows.
• Strong experience with immuno-electron microscopy.
• Experience operating and troubleshooting EM instruments.
• Someone who communicates well, works collaboratively, and is comfortable supporting multiple projects.

Nice to Have

• Experience working in a shared resource or core facility.
• Experience with, or strong interest in learning: Correlative Light and Electron Microscopy (CLEM)
• Focused Ion Beam-SEM (FIB-SEM)
• Cryo-electron microscopy (cryo-EM)
• Familiarity with image analysis tools.

What Makes Someone Successful in This Role

You’re a team player who enjoys working with a range of scientists and projects. You’re curious and motivated to learn new techniques and technologies. You’re organized, detail‑oriented, and take pride in producing high‑quality data. You can balance multiple priorities without losing track of the details.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: [e-mail]

This role has a market‑competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range $70,000 — $80,000 USD