Downstream Process Development, Engineer II

Scorpion Therapeutics; Lexington (MA); On-site; USD 72,000 - 113,000; Full time

Benefits offered by this job

Medical/dental/vision

401(k)

Tuition reimbursement

Paid time off

Job summary

Scorpion Therapeutics in Lexington, MA is seeking a Process Development Technician to execute chromatography, harvest, UF/DF, and viral clearance experiments and support downstream development across micro, bench, and pilot scales.

You will maintain laboratory equipment, document work in electronic laboratory notebooks with clear records, perform basic data analysis, and prepare technical summaries and study updates, following established procedures and safety requirements.

Qualifications

• Associate or bachelor's in a related field with 2+ years of experience.
• Experience with chromatography, harvest, UF/DF, and viral clearance.
• Ability to analyze data and present results clearly in writing.
• Experience with electronic laboratory notebooks.
• Familiarity with lab/quality requirements and following procedures.
• Some process development/protein purification experience.

Responsibilities

• Execute chromatography, harvest, UF/DF, and viral clearance experiments.
• Support downstream process development across micro, bench, and pilot scales.
• Maintain laboratory equipment and ensure instrument readiness.
• Collaborate with senior process engineers to plan and execute studies.
• Document work in electronic laboratory notebooks with clear records.
• Perform basic data analysis to review trends and support conclusions.
• Prepare technical summaries, study updates, and written materials.
• Follow established procedures and safety requirements.
• Contribute to continuous improvement of workflows and data capture.
• Assist with small projects under close supervision.

Skills

Chromatography

Data analysis

Electronic lab notebooks

Technical writing

Process development

Protein purification

AI-enabled analysis workflow

Education

Associate degree or Bachelor's in chemical engineering, chemistry, biochemistry, biotechnology, or related field

Tools

UF/DF equipment

Bioreactor control systems

ELN software

Process development software

Job description

Responsibilities

• Execute chromatography, harvest operations, ultrafiltration/diafiltration (UF/DF), and viral clearance experiments (may support bioconjugation).
• Support downstream process development across micro, bench, and pilot scales.
• Maintain laboratory equipment and ensure instrument readiness.
• Collaborate with senior process engineers to plan and execute larger experiments/study activities.
• Document work in electronic laboratory notebooks with clear, complete, timely records.
• Perform basic data analysis to review trends/conditions and support conclusions.
• Prepare technical summaries, study updates, and written materials.
• Follow established lab and process development procedures, including quality and safety requirements.
• Contribute to continuous improvement (workflows, data capture, experimental execution).
• Assist with small projects/specific tasks under close supervision.

Qualifications

• Associate degree with 2+ years relevant experience, or bachelor’s degree with relevant experience, in chemical engineering, chemistry, biochemistry, biotechnology, or related field.
• Experience with chromatography, harvest, UF/DF, and viral clearance steps.
• Comfort with digital tools and openness to AI-enabled processes for analysis/documentation/workflow improvement.
• Experience with basic bioprocess control systems.
• Experience using electronic laboratory notebooks.
• Ability to perform basic data analysis and present results clearly in writing.
• Familiarity with technical writing and laboratory/quality requirements.
• Ability to follow detailed procedures and maintain accurate records under close supervision.
• Some relevant experience in process development/protein purification.

Compensation/Benefits (as listed)

• U.S. base salary range: $71,800–$112,860; may be eligible for incentives and benefits (medical/dental/vision, 401(k), disability, life insurance, tuition reimbursement, paid time off, etc.).