Downstream CQV Engineer - 173962 - 174862

Piper Companies; Holly Springs (MS); On-site; USD 100,000 - 140,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k)

Job summary

Piper Companies is seeking a Downstream CQV Engineer for an onsite, six-month contract based in Holly Springs, NC. The role emphasizes commissioning and qualification activities across multi-building production environments, with a focus on downstream systems and utilities.

The ideal candidate has 2–10 years of CQV/validation experience in large-scale manufacturing, familiarity with Kneat, and a mechanical/engineering background to inspect and troubleshoot equipment.

Qualifications

• 2–10 years of hands-on CQV/validation experience in large-scale manufacturing environments.
• Experience with downstream processing equipment, ultrafiltration preferred.
• Mechanical or engineering background with ability to inspect and troubleshoot equipment.
• Familiarity with installation verification, utilities qualification, and system turnover processes.
• Experience with electronic validation systems (e.g., Kneat) is a plus.

Responsibilities

• Execute CQV activities for downstream manufacturing systems and utilities.
• Review drawings, P&IDs, and system documentation to support field execution.
• Perform hands-on testing, troubleshooting, and field walkdowns for large-scale equipment.
• Collaborate with engineering, operations, and quality teams to meet project timelines.
• Develop and complete electronic documentation and turnover packages per internal and regulatory standards.

Skills

CQV experience

Validation engineering

Mechanical engineering

Troubleshooting

Education

Engineering degree

Tools

Kneat

Job description

Piper Companies is seeking a Downstream CQV Engineer to join a growing organization within the life sciences and biopharmaceutical manufacturing industry. This is an onsite, 6‑month contract role with potential extensions, based in Holly Springs, NC. The Downstream CQV Engineer will support large‑scale manufacturing operations with a primary focus on downstream systems, utilities, and commissioning and qualification activities across a multi‑building production environment.

Responsibilities of the Downstream CQV Engineer:

• Execute commissioning, qualification, and verification (CQV) activities for downstream manufacturing systems and utilities
• Support installation verification and field execution through the review of drawings, P&IDs, and system documentation
• Perform hands‑on testing, troubleshooting, and field walkdowns for large‑scale equipment including pumps, filters, valves, and piping systems
• Collaborate with engineering, operations, and quality teams to resolve issues and maintain project timelines across multiple manufacturing suites
• Assist in the development and completion of electronic documentation and turnover packages, ensuring compliance with internal and regulatory standards

Qualifications for the Downstream CQV Engineer:

• 2-10 years of hands‑on experience in CQV, validation, or engineering within large‑scale manufacturing environments
• Experience working with downstream processing equipment; ultrafiltration experience strongly preferred
• Mechanical or engineering‑focused background with the ability to inspect, troubleshoot, and work directly with equipment and instrumentation
• Familiarity with installation verification, utilities qualification, and system turnover processes
• Experience with electronic validation systems (e.g., Kneat) is a plus

Compensation for the Downstream CQV Engineer:

• Salary Range: $100,000 - 140,000/year (USD)
• Comprehensive Benefits: Medical, Dental, Vision, 401(k), and applicable sick leave

Keywords: CQV engineer, commissioning, qualification, validation, downstream processing, ultrafiltration, IV, P&IDs, utilities qualification, large scale manufacturing, biopharmaceuticals, GMP, mechanical engineering, process equipment, pumps, filters, valves, Kneat, system turnover, field execution, equipment qualification, biotech manufacturing, water systems, UF systems.

This position opened for applications on August 21st, 2026, and will remain open for at least 30 days from the posting date.

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