Dissolution & Biopharm Modeling Scientist

BioSpace; Indianapolis (IN); Vor Ort; USD 66.000 - 172.000; Vollzeit

Benefits dieser Stelle

Company bonus

Comprehensive benefits

Zusammenfassung

Lilly in Indianapolis, IN, is seeking a driven scientist to advance analytical chemistry and biopharmaceutics within the Synthetic Molecule Design and Development (SMDD) group. You will contribute to drug substance and product development from early research through commercialization, collaborating across functions to deliver robust analytical solutions.

The role emphasizes hands-on method development and validation, regulatory understanding, and leadership in cross-functional teams, with travel

Qualifikationen

• Understanding analytical techniques and methods for characterizing physicochemical properties of drug molecules and performance of drug products (e.g., HPLC, UV, NIR, dissolution).
• Strong leadership, supervisor, teamwork, communication and writing skills.
• Demonstrated experience with development, validation, and transfer of analytical methods, especially dissolution, UV-Vis and HPLC.
• Hands‑on experience operating and troubleshooting automated dissolution systems, including autosamplers, fraction collectors, online UV/fiber‑optic analysis and hardware/instrument control software.
• Knowledge of biopharmaceutics, pharmacokinetic principles, formulation development and drug product factors impacting in vivo performance.

Aufgaben

• Develop analytical methods and conduct experiments to aid early clinical formulation development to enable drug delivery of a broad range of synthetic drug molecules.
• Collaborate with formulation scientists to design experiments and guide selection and characterization of formulations for pre-clinical and early clinical drug candidates.
• Partner with modeling scientists, analytical chemists, pharmaceutical scientists, and engineers to identify the appropriate drug form, formulation, and process characteristics for performance.
• Identify and mitigate technical risks for the performance and production of clinical and commercial drug products.
• Oversee instrument qualification, calibration, and preventive maintenance of dissolution equipment, and coordinate with vendors to minimize downtime.
• Author key regulatory documents demonstrating understanding of product performance control strategy and biopharmaceutics risk mitigation.

Kenntnisse

Analytical chemistry

Leadership

Communication

Writing skills

Teamwork

Ausbildung

B.S. in Chemistry/Biochem/Pharmaceutical Science

Tools

HPLC

UV-Vis

Dissolution equipment

Analytical method transfer

Jobbeschreibung

Lilly in Indianapolis, IN, is seeking a driven scientist to advance analytical chemistry and biopharmaceutics within the Synthetic Molecule Design and Development (SMDD) group. You will contribute to drug substance and product development from early research through commercialization, collaborating across functions to deliver robust analytical solutions.

The role emphasizes hands-on method development and validation, regulatory understanding, and leadership in cross-functional teams, with travel