Director RTSM

EPM Scientific; Philadelphia (Philadelphia County); Hybrid; USD 190,000 - 220,000; Full time

Benefits offered by this job

Bonus

Equity

Hybrid work

Job summary

EPM Scientific in the Greater Philadelphia Area is seeking a strategic leader to head RTSM. This hybrid role (2 days onsite) offers a base salary of $190,000–$220,000 plus bonus and equity terms.

You will lead RTSM/IRT strategy across Phase I–IV global clinical studies, partnering with Clinical Operations, Biostatistics, Data Management, and Regulatory Affairs, while overseeing risk, forecasting, and contingency planning related to trial supply.

Qualifications

• 8+ years of RTSM/IRT or clinical supply chain experience in pharma or CRO.
• Global trial experience across Phases I–IV with randomization and supply strategy.
• Strong knowledge of GxP, blinding, and investigational product management.
• Experience managing RTSM vendors, systems, validation, and cross-functional stakeholders.
• Demonstrated leadership, stakeholder influence, and driving operational excellence.

Responsibilities

• Lead RTSM and IRT strategy across Phase I-IV global clinical studies.
• Partner with Clinical Operations, Biostatistics, Data Management, Regulatory Affairs, and vendors.
• Oversee risk management, forecasting, and contingency planning for trial supply.
• Drive continuous improvement, RTSM governance, KPIs, and performance metrics.
• Build and mentor a high-performing team and manage vendor relationships.

Skills

RTSM/IRT leadership

Clinical supply chain

Cross-functional collaboration

Vendor management

Team leadership

Job description

Greater Philadelphia Area (Hybrid, 2 days/week onsite)

$190,000 - $220,000 Base + Bonus + Equity

Company Overview

Our client is a globally recognized biopharmaceutical organization committed to advancing innovative medicines and vaccines across multiple therapeutic areas. With a strong pipeline spanning early and late-stage development, they combine cutting-edge technology, operational excellence, and patient-centric thinking to bring transformative therapies to market. As they continue investing heavily in clinical development capabilities, they are seeking a strategic leader to head their RTSM function.

Responsibilities

• Lead RTSM and IRT strategy across Phase I-IV global clinical studies, ensuring efficient randomization and investigational product supply management.
• Partner with Clinical Operations, Biostatistics, Data Management, Regulatory Affairs, and external vendors to deliver seamless trial execution.
• Oversee risk management, forecasting, and contingency planning related to trial supply and patient randomization activities.
• Drive continuous improvement initiatives, including RTSM governance, KPIs, performance metrics, and operational efficiencies.
• Build, mentor, and lead a high-performing team while managing key vendor relationships and escalations.

Qualifications

• 8+ years of RTSM, IRT, clinical supply chain, or related clinical systems experience within pharma or CRO environments.
• Proven experience supporting global clinical trials across multiple phases with responsibility for randomization and trial supply strategies.
• Strong understanding of clinical operations, blinding methodologies, investigational product management, and GxP requirements.
• Experience overseeing RTSM vendors, system implementations, validation activities, and cross-functional stakeholder management.
• Demonstrated leadership experience managing teams, influencing senior stakeholders, and driving operational excellence initiatives.