Director, Protein Analytics & Characterization

Keros Therapeutics; Lexington (MA); On-site; USD 180,000 - 320,000; Full time

Job summary

Keros Therapeutics is seeking an expert in Analytical Science and Protein Characterization to join our team as Director of Analytical Development, leading the analytical strategy, method development and characterization for our protein pipeline.

The ideal candidate will have hands-on laboratory expertise in modern analytical chemistry, exceptional organizational skills, and a proven ability to translate complex data into actionable scientific decisions while building productive partnerships

Qualifications

• Expert in Analytical Science and Protein Characterization with hands-on lab experience.
• Proven ability to translate complex data into actionable scientific decisions.

Responsibilities

• Lead analytical development strategy for early to late-stage biologics programs, including Pre-Clinical, Phase I and Phase II/III
• Develop the strategic implementation of increasing levels of structural, physical, and advanced protein characterization in phase appropriate manner
• Serve as the subject‑matter expert in protein characterization and stability for phase‑appropriate development of the pipeline
• Partner with Manufacturing, Process Development, and Quality teams to define and implement phase‑appropriate analytical methods, specifications, and control strategies to support DS and DP
• Advise and oversee CDMOs' analytical method development, transfer, and validation
• Collaborate with CDMOs and CROs to develop and optimize a range of analytical assays for the release and characterization on a series of fusion protein and mAb biologics at each stage from preclinical to commercial launch
• Provide oversight of CDMOs and external testing laboratories, ensuring timelines, data quality, and compliance
• Ensure analytical methods and specifications are scientifically justified, phase appropriate, and compliant with applicable compendial standards and regulatory guidelines
• Support comparability, stability, and characterization strategies for process changes and scale‑up

Job description

Keros Therapeutics is seeking an expert in Analytical Science and Protein Characterization to join our team as Director of Analytical Development, leading the analytical strategy, method development and characterization for our protein pipeline.

The ideal candidate will have hands-on laboratory expertise in modern analytical chemistry, exceptional organizational skills, and a proven ability to translate complex data into actionable scientific decisions while building productive partnerships