Director, Project Management & Strategic Operations (Cystic Fibrosis)

MFS Investments; Boston (MA); Hybrid; USD 185,000 - 278,000; Full time

Job summary

Vertex Pharmaceuticals in Boston, MA is seeking a Director, Project Management & Strategic Operations (Cystic Fibrosis) to partner with a Disease Area Executive and drive cross-functional initiatives. You will lead strategic projects, create executive-level materials, and oversee KPI dashboards.

Ideal candidates bring 10+ years in strategy and project management within biopharma, with an advanced degree (MBA/PhD/MD) preferred and a track record of delivering impact in fast-paced environments.

Qualifications

• Bachelor's degree required; advanced degree preferred (MBA/PhD/MD).
• 10+ years of progressive strategy, PM, or corporate operations experience in healthcare/biopharma.

Responsibilities

• Partner with Disease Area Executive to lead strategic projects and initiatives.
• Coordinate cross-functional teams and attend key meetings on behalf of DAE.
• Develop dashboards and tools to report KPIs and ROI for initiatives; drive actionable insights.
• Produce high-impact executive presentations and lead after-action reviews for continuous improvement.

Skills

Executive communication

Cross-functional collaboration

Project management

Strategic thinking

Data analysis (Excel)

Education

Bachelor's degree

MBA/PhD/MD or equivalent

Tools

Excel

PowerPoint

Job description

# Director, Project Management & Strategic Operations (Cystic Fibrosis)Vertex PharmaceuticalsBoston, MAFull-TimeOct 15, 2026Pharmaceutical## Job Description**Job Description****General Summary:** Vertex is seeking a talented strategic colleague to serve in a critical role supporting the Disease Strategy Team Program Office in the Office of the CEO. The Strategy & Operations Director will partner closely with a Disease Area Executive (DAE) to drive special initiatives to support a particular DST. We are seeking a candidate that has a strong track record in strategic roles, along with cross functional collaboration and effective communication skills to apply for this opportunity.**Key Duties and Responsibilities:** • Partners with DAE to lead strategic projects and high-profile initiatives • Act as a liaison between cross functional colleagues to ensure alignment and coordination on a wide variety of cross-functional initiatives; Attends selected meetings on behalf of DAE • Develops dashboards or other tools for reporting of KPIs, monitors ROI of key initiatives and identifies focus areas to drive action that accelerates our plan • Drives the development of high-impact executive presentations • Leads after action reviews of critical projects; provide recommendations for improvement of processes and systems Knowledge and Skills: • Outstanding communication of information and ideas (written, PowerPoint, verbal), to varied audiences including senior and executive leadership • Analytical, able to glean insights from data using excel and other tools, and communicate in a compelling, visual way • Strong collaboration skills, with an ability to influence multiple stakeholders; builds mutual trust, respect and cooperation among team members • Proven project management skills, including scenario analysis, business acumen and the ability to manage multiple tasks and priorities; adapt to new projects rapidly and effectively • Strategic thinker with a track record of driving results • Self-motivated; acts independently and prioritizes appropriately; embraces unexpected changes or challenges and drives to improved solutions in a fast-paced environment • Proven ability to work in and influence a cross-functional team promoting collaboration and high performing team behaviors with an unwavering focus on what is best for the patients we serve • Consistently displays sound ethics, good judgment and demonstrates Vertex’s core values • Strong biopharmaceutical drug discovery and development acumen across multiple disciplines**Education and Experience:** • Bachelor's degree • Advanced degree (MBA, PhD, or MD) or comparable experience preferred • Typically 10+ years of progressive, relevant experience with demonstrated experience in strategy, project management, and organizing and directing multiple teams and departments in healthcare/biopharmaceuticals At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.**Pay Range:**$185,400 - $278,200**Disclosure Statement:**The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Flex Designation:**Hybrid-Eligible Or On-Site Eligible**Flex Eligibility Status:**In this Hybrid-Eligible role, you can choose to be designated as: 1. **Hybrid**: work remotely up to two days per week; **or select** 2. **On-Site**: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.#LI-Hybrid