Director, Disease Strategy Finance

MFS Investments; Boston (MA); Hybrid; USD 181,000 - 271,000; Full time

Benefits offered by this job

Annual bonus

Annual equity awards

Comprehensive benefits

Job summary

Vertex Pharmaceuticals in Boston, MA seeks a Director of FP&A, DST Finance to partner with Disease Area Executives and drive strategic financial planning across multiple disease strategies. You will lead analyses, valuations, and cross-functional budgeting to influence executive decisions and resource allocation.

Ideal candidates bring 10+ years in biotech FP&A or related fields, advanced modeling skills, and strong communication to present complex insights to senior stakeholders with a focus on

Qualifications

• Bachelor’s degree in finance, business, economics or accounting.
• MBA and/or other advanced degree preferred.
• 10+ years in FP&A, strategy, business development or related biotech roles.

Responsibilities

• Represents Finance in DSTs and drives financial analyses and reporting.
• Provides strategic decision support for business cases and planning scenarios.
• Partnership with Disease Area Executives, program managers and cross-functional teams.
• Lead process improvements and drive cross-functional efficiency.
• Act as center of excellence for modeling, valuation and ad hoc analysis.

Skills

Financial modeling

Strategic thinking

Communication skills

Excel

PowerPoint

C-Suite partnering

Education

Bachelor's degree in finance, Business, Economics or Accounting

MBA

Tools

Hyperion

Job description

# Director, Disease Strategy FinanceVertex PharmaceuticalsBoston, MAFull-TimeSep 11, 2026Accounting## Job Description**Job Description**Vertex is growing at a rapid pace with challenging and exciting opportunities for motivated professionals who are keen to contribute to the Vertex mission to invest in scientific innovation to create transformative medicines for people with serious diseases. Our finance function is integral to achieving our company’s strategic goals, providing critical insights and analysis in support of decision-making across the organization. By joining our function, you will become part of a fast-moving, forward-thinking team to support the ongoing growth of a leader in the biotechnology industry.The **Director of FP&A, DST Finance** is a key member of Vertex's Financial Planning & Analysis organization, providing financial direction and strategic insights to cross-functional leaders. This role will partner closely with **Disease Area Executives** for assigned **Disease Strategy Teams** (“DSTs”) to help define and deliver against our goals. This role will provide strategic decision support, influence decisions and identify opportunities to invest, save costs and mitigate risks on a global basis. The role will also conduct corporate-level cross-functional valuations, modeling and other analysis to help drive our decision-making process.**Key Duties and Responsibilities:*** Represents Finance in DSTs across the organization, coordinates appropriate financial analyses, and drives the development of reporting and analytics for each program.* Provides strategic decision support to enable clear understanding of financial impacts of potential business cases and/or planning scenario for multiple diseases at different stages of development.* Partners with Disease Area Executives, Program Managers and a wide range of core members from different areas of Vertex represented on Disease Strategy Teams.* Coordinates with other members of the finance team including Corporate, BD, R&D, Commercial, BSMO Finance as well as other CFO organization areas such as Accounting, Tax, and Treasury, promoting strong communication and collaboration across.* Proactively identifies, designs and implements enhancements to existing processes to drive efficiency across the teams.* Represents DST Finance as a center of excellence for all modeling, valuation and ad hoc analysis used for a wide range of decisions, including presentations at Executive Committee level meetings.* Opportunity to help build a high-performing Finance team that meets increasing needs and requirements across the business and helps drive the overall organization forward.**Basic Requirements:*** Bachelor’s degree in finance, Business, Economics or Accounting required. MBA and/or other advanced degree preferred.* 10+ years of experience in FP&A, Strategy, Business Development, Portfolio Management, or related roles within the biotech, pharma, or life sciences industry, with a focus on a deep understanding of drug discovery, development, manufacturing, regulatory, and commercialization.* Expert analytical and financial modeling skills to evaluate a broad range of financial questions – especially valuation and strategic planning.* Excellent communication and presentation skills, with the ability to influence stakeholders at all levels and a proven ability to present complex financial insights to senior stakeholders.* Demonstrated success in leading process improvement and change management initiatives.**Important Knowledge and Skills:*** Experience in healthcare, pharmaceuticals, biotech or consulting.* Business partnering with C-Suite and executive level members of the organization.* Strategic thinking and problem-solving.* Strong analytical and financial modeling skills to evaluate a broad range of financial questions – especially portfolio analysis, valuation, and complex business questions.* Expertise with Excel and PowerPoint; Working knowledge of Hyperion or similar enterprise planning tools.* Ability to lead and drive change in an evolving business environment, coordinating processes involving large numbers of people, complex systems, and tight deadlines to deliver innovative solutions.* Strong business acumen and judgment, and knowledge of the company's markets/products and industry trends.* Strong communication skills, both written and verbal, and an eagerness to collaborate with colleagues (within or outside of finance) in sharing insights and learnings and partnering to ensure timely execution of project plans.* Possesses a continuous improvement mindset, with flexibility and ability to adapt to change.**Flex Designation:****Hybrid-Eligible Or On-Site Eligible**Flex Eligibility Status:In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.**Pay Range:**$180,700 - $271,100**Disclosure Statement:**The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Flex Designation:**Hybrid-Eligible Or On-Site Eligible**Flex Eligibility Status:**In this Hybrid-Eligible role, you can choose to be designated as: 1. **Hybrid**: work remotely up to two days per week; **or select** 2. **On-Site**: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.#LI-Hybrid