Director, Program Management Office

Alkermes; Boston (MA); Hybrid; USD 212,000 - 240,000; Full time

Job summary

Alkermes is seeking a seasoned Program Manager to support the ALKS 4510 program, part of our orexin 2 receptor agonist portfolio strategy. The role translates strategy into actionable plans, navigates complexity, and enables timely decision-making and delivery across the organization.

The position follows a hybrid work model with 60% in-office and 40% from home, based at our Waltham, MA office at least 3 days per week; fully remote work is not available.

Qualifications

• 12+ years of pharmaceutical product development experience.
• Strong verbal and written communication, time/resource management, attention to detail.
• BS/MS in a scientific or engineering discipline.

Responsibilities

• Facilitate development and execution of integrated program plans, including goals, activities and cross-functional linkages.
• Manage meetings with proactive agendas and well-documented minutes; support planning, problem solving and alignment.
• Develop and maintain program budgets, timelines, and reporting tools used by team and senior management for governance.
• Cultivate enterprise mindset and drive cross-functional prioritization and decision making.
• Contribute to enhancement of program management systems, tools, and processes.

Skills

Verbal communication

Written communication

Time management

Attention to detail

Interpersonal skills

Organization

Education

BS/MS in science or engineering

Tools

MS Project

MS Excel

MS PowerPoint

Job description

Job Description

Alkermes is seeking a seasoned Program Manager to support our ALKS 4510 program, a key component of our orexin 2 receptor agonist portfolio strategy targeting fatigue associated with neurological disorders. The Program Manager will enable seamless execution of this dynamic development program by translating strategy into actionable plans, navigating complexity, and facilitating effective decision-making and delivery across the organization.

We're looking for an individual who values the team dynamic, is organizationally savvy, excels in a matrixed-management/leadership environment, and thrives at connecting detailed execution with strategic priorities.

Alkermes has recently adopted a hybrid working environment to support and meet the needs of employees and this role will operate in a flexible environment with 60% of time in the office and 40% from home. This position is eligible for the hybrid workplace model, requiring work to be completed onsite at our Waltham, MA office at least 3 days per week. This role is not eligible for fully remote work.

Responsibilities

• Facilitating development and execution of integrated program strategic and operational plans, including:
  
  
  
  • Identification and monitoring of critical program goals, activities, and cross-functional linkages
  
  
  • Optimization of plans by challenging assumptions, evaluating opportunities to address constraints and gaps, and incorporating of new inputs as the program progresses
  
  
  • Proactive discussion and management of potential risk areas, including endorsement and implementation of aligned mitigation and/or contingency plans
  
  
  
  


• Providing strong project and program management support to the product team and key sub-teams by:
  
  
  
  • Managing and facilitating meetings with proactive agenda planning and well-documented minutes, designed to support effective planning, problem solving and alignment
  
  
  • Developing and maintaining program budgets, timelines, and reporting tools/documents used by the team and senior management to ensure effective coordination, transparent and open communication, and disciplined governance
  
  
  • Cultivating an enterprise mindset within the team and driving strong cross-functional prioritization and decision making
  
  
  • Leading with an innovative, solution-oriented approach to ensure issues are resolved and communicated/escalated as needed
  
  
  
  


• Contributing to enhancement and innovation of our program management systems, tools, and processes to support the evolving needs of our teams and the broader business

Qualifications

Basic Requirements

• BS/MS in a scientific or engineering discipline, with 12+ years of relevant pharmaceutical product development experience


• Exceptional verbal/written communication, time/resource management, attention to detail, and interpersonal and organization skills

Preferred Requirements

• Prior experience managing cross-functional teams across the drug product lifecycle continuum from research through early-stage development and into late-stage development


• Prior experience maintaining program strategic plans and timelines with budgetary management responsibility


• Prior experience working on regulatory documents, interactions and filings


• Expert knowledge of MS Project (or equivalent), MS Excel, and MS PowerPoint

The annual base salary for this position ranges from $212,000 to $240,000. In addition, this position is eligible for an annual performance pay bonus. Exact compensation may vary based on skills, training, knowledge, and experience. Alkermes offers a competitive benefits package. Additional details can be found on our careers website: www.alkermes.com/careers#working-here

About Us

Alkermes applies its decades of deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. A global biopharmaceutical company, headquartered in Ireland with U.S. locations in Massachusetts and Ohio, we seek to make a meaningful difference in the way people manage their diseases. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.

Why join Team Alkermes?

We are proud to have been recognized as an employer of choice by many national organizations. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts’ Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.

Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any qualified applicant or employee because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, gender expression and identity, disability, genetic information, veteran status, military status, application for military service or any other characteristic protected by local, state or federal law. Alkermes also complies with all work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Alkermes is an E-Verify employer.