Director, Process Chemistry

Scorpion Therapeutics; United States; Remote; USD 250,000 - 380,000; Full time

Benefits offered by this job

Remote work with travel

Job summary

Scorpion Therapeutics is seeking a Director, Process Chemistry in API Development to lead API/Intermediate/RSM manufacturing at CMOs, directing synthesis route development, process optimization, tech transfer, and process validation for clinical and commercial supply.

You will oversee CMO operations, collaborate with R&D on lead optimization, and guide process characterization and regulatory filings in a regulated environment, with potential remote work and ~travel.

Qualifications

• PhD in Organic Chemistry or Chemical Engineering with 5+ years in API process development.
• Experience leading development teams and managing CMO operations in regulated environments.
• Strong leadership and communication skills; ability to collaborate cross-functionally.

Responsibilities

• Oversee CMO operations and external manufacturing for APIs.
• Collaborate with R&D on lead optimization and scale-up.
• Manage tech transfer and process improvements.
• Provide technical review of quality documentation.
• Lead process characterization efforts.

Skills

NCE synthesis

Physical organic chemistry

Validation

Quality systems

Regulatory filings

Communication

Leadership

Education

PhD in Organic Chemistry or Chemical Engineering

Job description

Role:

Director, Process Chemistry in API Development, responsible for managing API/Intermediate/RSM manufacturing at CMOs, including synthesis route development, process optimization, tech transfer, and process validation.

Objectives:

support early-stage process identification, scale-up, and manufacturing strategy to enable clinical and commercial supply for serious diseases.

Responsibilities:

oversee CMO operations, collaborate with R&D on lead optimization, manage tech transfer and process improvements, provide technical review of quality documentation, and lead process characterization efforts.

Qualifications:

PhD in Organic Chemistry or Chemical Engineering with 5+ years of experience in API process development, including managing development teams and CMO operations in regulated environments.

Skills:

expertise in NCE synthesis, physical organic chemistry, validation, quality systems, and regulatory filings; strong communication and leadership skills.

Preferred:

10+ years of experience across full API development lifecycle, including marketed products.

High-Value:

biopharma, API synthesis, process development, early to late-stage development, regulated environment, global regulatory compliance, remote work with occasional travel (~10%).

Collaboration:

Collaboration with research, regulatory, and manufacturing teams; no specific therapeutic focus indicated.