Director, Preclinical Safety & Toxicology Operations

Nurix Therapeutics; Brisbane (CA); On-site; USD 221,000 - 253,000; Full time

Job summary

Nurix Therapeutics, based in Brisbane, CA, seeks a Director of Preclinical Safety and Toxicology Operations to drive planning and execution of nonclinical safety activities across Research and Early Development. The role oversees timelines, budgets, CROs, and cross-functional coordination for a portfolio of degrader programs.

The ideal candidate partners with toxicology leads, project teams, and senior leadership to turn complex study pipelines into actionable milestones, ensuring IND readiness

Qualifications

• MS or PhD in a life sciences discipline (toxicology, pharmacology, biology, chemistry, pharmaceutical sciences, or related).
• Preferred: PMP or formal project management credential.

Responsibilities

• Scope, design, and schedule GLP and non-GLP safety studies; manage CROs and vendors; coordinate contracts and budgets.
• Develop and maintain integrated program plans across chemistry, DMPK, pharmacology, safety, CMC, and regulatory.
• Lead cross-functional project teams; maintain dashboards, risk registers, and milestone tracking.
• Prepare materials for governance meetings and IND-related planning; support go/no-go decisions and IND timing.

Skills

Project management

Communication

Leadership

Organizational skills

Ambiguity handling

Education

MS or PhD in life sciences

PMP credential

Tools

MS Project

Smartsheet

Planisware

AI tools

Job description

Nurix Therapeutics, based in Brisbane, CA, seeks a Director of Preclinical Safety and Toxicology Operations to drive planning and execution of nonclinical safety activities across Research and Early Development. The role oversees timelines, budgets, CROs, and cross-functional coordination for a portfolio of degrader programs.

The ideal candidate partners with toxicology leads, project teams, and senior leadership to turn complex study pipelines into actionable milestones, ensuring IND readiness