Director, Oncology Translational Medicine Project Manager

GlaxoSmithKline; Upper Providence (Delaware County); Hybrid; USD 190,000 - 316,000; Full time

Benefits offered by this job

Health care

Retirement benefits

Paid holidays

Job summary

GSK seeks a Director, Oncology Translational Medicine Project Manager to lead strategic initiatives across translational medicine, biomarker and diagnostic programs within the oncology portfolio.

You will oversee external alliances, regulatory planning, budget management, and cross-functional collaboration with Clinical Operations, Data Management, Regulatory, and Finance to advance oncology assets.

Qualifications

• Bachelor's degree in biological sciences or related discipline.
• Strong background and experience in Oncology.
• 10+ years of project/program or alliance management experience supporting biomarker and/or diagnostic development programs.
• Knowledge of drug discovery and development, clinical trial design, Dx development, and regulatory submissions.
• Experience with MS Project, MS Office, and remote meeting tools; familiarity with AI technologies.

Responsibilities

• Lead operational oversight of external alliances and academic collaborations focused on biomarker discovery and acceleration.
• Support scientific and business leads in alliance objectives, scope, and success metrics.
• Coordinate meeting forums with partners, ensuring decisions, actions, and risks are documented and followed.
• Translate the collaboration strategy into integrated project plans (scope, milestones, dependencies, risks).
• Track alliance workplans for biomarker discovery and assay development; align with internal needs and timelines.
• Monitor progress against milestones and KPIs; coordinate course-corrections as needed.
• Support contracting activities, SOW development, and oversight for external alliances.
• Coordinate alliance-related budgets: track spend, PO/invoice workflows, and scope reconciliation.
• Monitor progress and escalate issues; drive mitigations across cross-functional teams.
• Schedule and run alliance and project team meetings; track decisions and actions to closure.
• Maintain integrated plans for CPMS components of regulatory submissions across Oncology portfolio.
• Support regulatory submissions readiness and CPMS documentation.

Skills

Analytical Thinking

Clinical Data Interpretation

Clinical Data Review

Clinical Development

Clinical Trial Designs

Clinical Trials Monitoring

Digital Fluency

Drug Regulatory Affairs

Executive Presence

Hematology Oncology

Learning Agility

Matrix Leadership

Real World Evidence

Scientific Presentations

Education

Bachelor's degree in biological sciences

Tools

Microsoft Project

Microsoft Office

MS Teams

WebEx

Job description

Business Introduction

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.

Find out more:

Our approach to R&D

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.

Director, Oncology Translational Medicine Project Manager

Job Purpose:

The Oncology Translational Medicine (OTM) Planning & Execution team is a dedicated group of Scientific Operations, Project Management, and Alliance Management professionals that integrate, manage, and drive execution of OTM's biomarker and diagnostic strategies across GSK's global Oncology portfolio.

The Director, Oncology Translational Medicine Project Manager, will provide high-quality project management support to the delivery of OTM strategic initiatives, and to the OTM Leadership Team, including the Clinical & Translational Biomarkers, Precision Diagnostics, and Clinical Pharmacology Modelling and Simulation (CPMS) divisions. Accountabilities include, but are not limited to, management and oversight of translational research alliances and collaborations, regulatory submission planning and tracking, and coordination of diagnostic target profiles. The OTM Project Manager oversees strategic and operational management of external alliances (e.g. academic centres) for biomarker discovery and acceleration. The OTM Project Manager drives the planning and tracking of portfolio‑level CPMS‑related regulatory submissions, ensuring high‑quality data packages and documentation are delivered to support oncology asset development and approvals. This role also coordinates activities related to target diagnostic profiles.

The Director is accountable for planning, execution and stakeholder coordination across OTM and the Oncology Research Unit, Clinical Operations, Data Management, Regulatory, and Finance, as well as external collaborators. The Director will schedule and run project meetings, maintain dashboards and decision logs, oversee budgets, contracts, and resource needs, manage risks and interdependencies, support regulatory submissions and compliance requirements, and deliver clear reporting to the OTM LT.

Responsibilities:

• Lead operational oversight of external alliances and academic collaborations focused on biomarker discovery and acceleration
• Support scientific and business leads in establishing alliance objectives, scope, and success metrics aligned with OTM and Oncology portfolio priorities
• Coordinate meeting forums with partners (joint project team, working groups), ensuring decisions, actions, and risks are clearly documented and followed through
• Translate the collaboration strategy and vision into integrated, detailed project plans (scope, milestones, critical paths, dependencies, risks)
• Track alliance workplans for biomarker discovery, assay development, etc., ensuring partner deliverables align with internal scientific needs and timelines
• Monitor performance against agreed milestones and KPIs (e.g. data generation, sample throughput); coordinate course-corrections where needed
• Support contracting activities, SOW development, and operational oversight for external alliances, in collaboration with Procurement and Study Leads
• Coordinate alliance‑related budgets: track spend vs. plan, support PO/invoice workflows, and reconcile against contracted scopes
• Monitor progress versus plan; proactively identify issues and interdependencies, elevate as needed, and coordinate cross‑functional mitigation plans
• Schedule, structure, and run alliance meetings and project team meetings (set agendas, pre‑reads, minutes, action logs), track and drive closure of decisions and actions
• Build and maintain integrated plans and tracking for CPMS components of regulatory submissions (data packages, reports, validation summaries) across the Oncology portfolio
• Support compliance with regulatory expectations by organizing CPMS documentation and tracking contributions to regulatory submissions
• Track status of required documents, reviews, and approvals; proactively identify gaps and risks to submission readiness and coordinate mitigation and escalation
• Coordinate the creation and maintenance of Diagnostic Target Profiles, including management of the associated database

Basic Qualifications:

• Bachelor's degree in biological sciences or related discipline.
• Strong background and experience in Oncology.
• Demonstrated experience and understanding and application of Project Management principles, concepts, practices, and standards.
• Minimum of 10 years of project/program or alliance management experience supporting biomarker and/or diagnostic development programs in the diagnostic, pharmaceutical, or biotech industry, with a solid understanding of the scientific operational needs, including outsourcing processes, vendor management, and scientific study plans.
• Knowledge and experience in drug discovery and development, clinical trial design, principles of clinical development, as well as Dx development, and regulatory submissions.
• Established expertise and hands‑on experience with Microsoft Project or equivalent, Microsoft office applications, remote meeting tools such as MS Teams, WebEx, etc. and a working understanding of innovative AI technologies (e.g., Claude, CoPilot, ChatGPT, GiGi, Jules, etc.).

Preferred Qualifications:

• Advanced scientific degree.
• PMP or PRINCE2 certification.
• Excellent process and project management skills gained in a matrix organization.
• Ability to manage and track projects to obtain desired business objectives.
• Experience with data, AI, or real‑world evidence initiatives.
• Highly effective communication (verbal, written, and presentation), negotiation, and facilitation skills; ability to work effectively with external partners and internal stakeholders at multiple levels.
• Ability to interact effectively across boundaries using influencing and relationship building skills.
• Ability to translate complex scientific and regulatory requirements into clear, executable plans and tracking frameworks: ability to proactively anticipate, identify and resolve issues and hurdles.
• Demonstrated ability to think strategically and execute multiple projects simultaneously.

#LI-GSK*

#Hybrid*

Skills

Analytical Thinking, Clinical Data Interpretation, Clinical Data Review, Clinical Development, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Regulatory Affairs, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations

If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $189,750 to $316,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at [e-mail].

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