Director of Information Technology

Avalo Therapeutics; Chesterbrook (PA); On-site; USD 130,000 - 160,000; Full time

Job summary

A clinical-stage biotech company in Chesterbrook is seeking a Director of IT to implement technology strategies and operations focused on compliance and innovation. This role requires extensive IT experience in a regulated environment and knowledge in cybersecurity and cloud architecture. The Director will manage infrastructure, ensure regulatory compliance, and support growth initiatives. Competitive compensation and a commitment to teamwork are offered.

Qualifications

• 10+ years of progressive IT experience in biotech or pharmaceutical environments.
• Strong knowledge of compliance frameworks (e.g. NIST CSF, SOX, GxP).
• Experience with Data Privacy and Data Loss Prevention.

Responsibilities

• Implement Avalo Information Security program aligned with business objectives.
• Manage cloud applications, services, networks, and servers.
• Oversee secure endpoint configuration and management.

Skills

Cybersecurity knowledge

Cloud architecture expertise

Problem-solving skills

Excellent communication

Customer-focused mindset

Technical savvy

Education

Technical or science degrees

Tools

Microsoft Azure

Job description

At Avalo (ahh-vah'-low), we are 100% focused on developing treatments for immune‑mediated inflammatory diseases with large unmet needs that affect millions worldwide. Our strategy is to develop medicines that target the IL‑1β pathway, which is a central driver of the inflammatory process. We share a commitment to teamwork, passion for science, and dedication to patients suffering from acute and chronic inflammatory disorders. Our collective expertise in discovery, development, and regulatory approvals is evidenced in our strong individual track records of advancing multiple therapeutic programs to successful commercialization.

Position Summary

The Director of IT will play a critical role in implementing our technology strategy and operations in a highly regulated biotech/pharmaceutical environment. This role requires a hands‑on leader who combines strategic vision with a willingness to roll up their sleeves and assist with day‑to‑day technical challenges. The ideal candidate will ensure compliance with industry regulations while driving innovation, efficiency, and security across functions. The person is accountable for the delivery of technical solutions from technology evaluation, implementation to maintenance. The person will be involved in technical design, development, and documentation of solutions as needed and actively involved in system configuration and enhancement.

Main Responsibility Areas

• Implement and continuously improve Avalo Information Security program aligned with business objectives and regulatory requirements (SOX, GxP, FDA, and other relevant regulatory standards). Ensure Avalo maintains a strong cyber posture, security first, and cyber aware culture.
• Ensure Avalo’s infrastructure and cloud computing are properly architected and scaled to support Avalo’s growth. Assist setting up cloud applications, services, networks, and servers as required.
• Manage infrastructure including Video/Audio conference systems, and data governance. Ensure infrastructure solutions are compliant with corporate policies/standards and relevant regulations.
• Ensure changes to Avalo Information Systems adhere to the regulatory and compliance requirement.
• Oversee secure endpoint configuration and management in collaboration with Managed Service Provider.
• Keep up‑to‑date with relevant technology supporting Avalo business to ensure fit‑for‑purpose, scalable technology implemented to support Avalo’s growth.
• Serve as the system owner and administrator of Avalo business systems ensure technology/systems properly managed and maintained. Partners with business owners ensure the proper control of system access and content management.
• Develop and configure solutions from conceptualization to stabilization using various computer platforms.
• Provide direct assistance to end users for computer, network, communication and software issues.

Education & Experience

• Technical or science degrees
• 10+ years of progressive IT experience, including leadership roles in regulated biotech or pharmaceutical environments.
• Strong knowledge of cybersecurity and compliance frameworks (e.g. NIST CSF, SOX, GxP).
• Expertise in Microsoft Azure, cloud architecture, and modern IT infrastructure.
• Experience with Data Privacy and Data Loss Prevention.
• Familiarity with AI technologies and their application in business processes.
• Exceptional problem‑solving skills and willingness to engage in hands‑on technical support.
• Excellent communication and interpersonal skills.

Additional Skills, Knowledge, And/or Abilities

• Proactive, adaptable, and customer‑focused mindset.
• Ability to balance strategic priorities with operational demands.
• Ability to deliver with limited resources and short timeline and manage multiple initiatives at once with good sense of priority setting.
• Strong ownership and sense of urgency in responding to business needs.
• Technical savvy with ability to quickly master new technology and system.
• Demonstrated technical, organizational, project management skills.
• Strong problem and issue resolution skills.

Onsite/Travel Requirement

The job requires communication with all employees during and after working hours as well as working with clients, contractors and other personnel. This position requires a minimum of three days onsite.

About Avalo Therapeutics

Avalo Therapeutics is a clinical stage biotechnology company fully dedicated to developing IL‑1β‑based treatments for immune‑mediated inflammatory diseases. Our lead asset, AVTX‑009, is in a Phase 2 clinical trial for hidradenitis suppurativa (HS). We’re also exploring additional opportunities to make an impact in prevalent indications that have significant remaining unmet needs. For more information about Avalo, please visit www.avalotx.com.

Attention: External Agencies and Placement Firms

A member of the Avalo Human Resources Department will contact an agency directly if an open position is eligible to be sourced from an outside recruiting service. Avalo does not accept unsolicited resumes from employment agencies for any employment opportunity. All agencies/recruiters must have a written agreement/SOW in place with Avalo and prior to submitting any resume or CV. All resumes must be submitted through the appropriate process. Any resumes submitted without an agreement and/or any resumes sent unsolicited through e‑mail accounts of Avalo employees will be considered outside of the appropriate process, do not imply or create any obligation on our part, do not impart any restrictions on Avalo with respect to the hiring of any persons whose resumes are so submitted and are not eligible for placement fees.