Director, Medical Information

Definium Therapeutics; United States; Remote; USD 230,000 - 290,000; Full time

Benefits offered by this job

Health insurance

401(k) with company match

Flexible time off

Wellness benefits

Job summary

Definium Therapeutics seeks a Director of Medical Information to lead strategy and operations, ensuring accurate, balanced scientific responses to healthcare professionals, patients, and caregivers. You will oversee external contact centers, vendors, and content quality in a fast-paced, compliant environment.

Reporting to Medical Affairs, you will drive cross-functional collaboration with Regulatory, Pharmacovigilance, and Clinical Development to align medical information with strategy and

Qualifications

• PharmD, PhD, MD, or another relevant advanced clinical or scientific degree.
• At least 7 years of pharmaceutical/biotech experience with 5+ years in Medical Information.
• Experience leading medical information operations and managing outsourced contact centers, vendors, budgets, and service agreements.
• Strong scientific writing, literature evaluation, and clinical data interpretation skills.
• Knowledge of scientific exchange, unsolicited off-label inquiries, safety reporting, and privacy; experience with medical information systems.
• Ability to lead across functions, manage competing priorities, and contribute to scientific and operational work.
• Psychiatry or neuroscience experience preferred.

Responsibilities

• Lead Medical Information activities aligned with Medical Affairs priorities, including planning, budgets, and resources.
• Manage medical information contact center vendors, including selection, contracts, service standards, training, quality reviews, and performance.
• Oversee standard response letters, FAQs, and customized responses to unsolicited inquiries, ensuring scientific accuracy and nonpromotional content.
• Manage inquiry workflows, content and inquiry systems, procedures, and quality metrics; drive continuous improvement.
• Serve as escalation point for complex requests and provide scientific guidance to vendors and internal colleagues.
• Collaborate with Pharmacovigilance and Quality on documentation, escalation, and reconciliation of safety reports and product quality complaints; support audit readiness.
• Coordinate with Clinical Development, Medical Affairs, Regulatory, Legal, and Compliance on content review and training.
• Analyze inquiry trends to identify unmet information needs and inform medical strategy.

Skills

Medical Information Leadership

Vendor Management

Scientific Writing

Regulatory Knowledge

Cross-functional Collaboration

Education

PharmD/PhD/MD or equivalent

Job description

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our leadproductcandidate,lysergidetartrate(ourproprietary orally disintegrating tablet form oflysergide(LSD) D-tartrate),represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided bythe recognitionthat patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to addresstheunderlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward - beyond better, into a boundless future. Join us!

The Director, Medical Information will lead the medical information strategy and operations, including oversight of external contact center partners. This role ensures accurate, balanced, and timely scientific responses to healthcare professionals, patients, and caregivers. The ideal candidate combines scientific expertise with operational leadership and a collaborative approach to managing vendors, content, and service quality.

Responsibilities

• Lead Medical Information activities aligned with Medical Affairs priorities, including departmental planning, budgets, and oversight of internal and external resources
• Manage medical information contact center vendors, including selection, contracts, service standards, training, quality reviews, and performance
• Oversee standard response letters, FAQs, and customized responses to unsolicited inquiries, ensuring scientific accuracy, appropriate balance, and nonpromotional content
• Manage inquiry workflows, content and inquiry systems, operating procedures, and quality metrics; drive continuous improvement
• Serve as the escalation point for complex requests and provide scientific guidance to vendors and internal colleagues
• Partner with Pharmacovigilance and Quality on documentation, escalation, and reconciliation of safety reports and product quality complaints; support audit readiness
• Collaborate with Clinical Development, Medical Affairs, Regulatory, Legal, and Compliance on content review, scientific training, and appropriate information exchange
• Analyze inquiry trends to identify unmet information needs and share insights that inform medical strategy and educational resources

Qualifications:

• PharmD, PhD, MD, or another relevant advanced clinical or scientific degree
• At least 7 years of pharmaceutical or biotechnology experience, including at least 5 years in Medical Information
• Experience leading medical information operations and managing outsourced contact centers, vendors, budgets, and service agreements
• Strong scientific writing, critical literature evaluation, and clinical data interpretation skills
• Knowledge of requirements for scientific exchange, unsolicited off-label inquiries, safety reporting, and privacy; experience with medical information systems
• Ability to lead across functions, manage competing priorities, and contribute directly to scientific and operational work
• Psychiatry or neuroscience experience preferred

Individual compensation within the range is determined based on factors such as relevant skills, experience, qualifications, scope of the role, and other legitimate business considerations. In addition to base salary, this role may be eligible for bonus and equity opportunities.

• We also offer a comprehensive benefits package including health insurance, 401(k) with company match, flexible time off and additional wellness benefits and perks. Learn more about our benefits on our Careers page.

The anticipated base salary range for this position is:

$230,000 - $290,000 USD