Director, Head of Predictive Modeling & Biopharmaceutics

Takeda; Boston (MA); Hybrid; USD 180,000 - 260,000; Full time

Benefits offered by this job

Hybrid work arrangement

Job summary

Scorpion Therapeutics seeks a leader to direct predictive modeling and biopharmaceutics in drug product development, with a focus on oral dosage forms.

You will build and guide a high-performing team, set standards, and drive innovation to improve development efficiency and risk mitigation. Based in Boston, MA, this full-time, hybrid role involves strategic collaboration across functions.

Qualifications

• PhD or MSc in pharmaceutical sciences, chemistry, mathematics, or engineering with extensive industry experience.
• Expertise in PBPK/PBBM, absorption, dissolution, IVIVC/IVIVR, and biopharmaceutics.
• Proven leadership in drug development, regulatory support, and cross-functional collaboration.

Responsibilities

• Lead scientific and strategic direction for predictive modeling and biopharmaceutics within drug product development.
• Oversee biopharmaceutics data interpretation and regulatory support.
• Influence regulatory submissions with modeling justifications and risk assessments.

Skills

PBPK/PBBM

Biopharmaceutics

Absorption

Dissolution

IVIVC/IVIVR

Leadership

Cross-functional collaboration

Communication

Education

PhD or MSc in pharmaceutical sciences/chemistry/mathematics/engineering

Job description

Role

Lead scientific and strategic direction for predictive modeling and biopharmaceutics within drug product development, focusing on oral dosage forms.

Responsibilities

• develop and execute modeling strategies supporting formulation design, bioavailability, and product performance;
• oversee biopharmaceutics data interpretation;
• influence regulatory submissions with modeling justifications;
• build and lead a high-performing team;
• establish standards and best practices;
• drive innovation to enhance development efficiency and risk mitigation.

Requirements

• PhD or Master's in pharmaceutical sciences, chemistry, mathematics, or engineering with 8-18+ years of industry experience;
• deep expertise in PBPK/PBBM, absorption, dissolution, IVIVC/IVIVR, and biopharmaceutics;
• proven leadership in drug development, regulatory support, and cross-functional collaboration;
• strong communication and decision‑making skills.

HighValue

focus on oral drug development, predictive modeling, biopharmaceutics, regulatory interactions, and leadership in a global biopharmaceutical context.

WorkSetup

based in Boston, MA; full-time, hybrid arrangement with no specified travel needs.