Director, Global Market Access

Alnylam Pharmaceuticals; Cambridge (MA); On-site; USD 210,000 - 284,100; Full time

Job summary

Alnylam Pharmaceuticals in Cambridge, MA is seeking a leader to own global pricing and market access for its Rare Disease portfolio and select pipeline assets. You will shape strategy, partner with commercial, medical, and policy teams, and ensure consistent access across regions.

The role requires deep experience in market access, pricing, payer engagement, and performance analytics, with a track record of leading cross-functional teams and presenting to senior leadership.

Qualifications

• Bachelor's degree required.
• MBA/MPH/PharmD or Health Economics/Outcomes Research preferred.
• 10+ years of commercial market access experience; 5+ years in rare disease.
• Substantial US, EU & Emerging Market experience with market access strategies, launch pricing, contracting, reimbursement, and distribution concepts for specialty products.
• Problem Solving & Innovation - unstructured strategy problems linked to revenue and profit.
• Proven ability to lead a high performing cross-functional team and execute amidst competing priorities.
• Strong written and verbal communication skills.
• Experience presenting to C-suite leaders with clarity and business focus.
• Strong business & scientific acumen, learning agility.
• Ability to influence & build relationships in a matrix environment.
• Ability to define, track, analyze key access metrics and make data-driven decisions.
• Ability to prioritize and manage multiple projects simultaneously.

Responsibilities

• Lead development of strategic access plans for inline brands and pipeline products, including access landscape, payer segmentation, and value proposition development.
• Communicate access-specific strategies to internal partners for brand planning.
• Develop market access strategy from a commercial viewpoint with cross-functional input.
• Champion priority access initiatives with meaningful business impact.
• Collaborate with Global and Regional Market Access Strategy teams to share learnings and drive franchise success.
• Serve as single-point-of-contact for all pricing strategy discussions for the P&EM unit.
• Develop partnerships with Regional Market Access, Value & Evidence Strategy, Pricing, Advocacy/Policy, and Legal teams to drive decisions.
• Lead payer value storytelling with clinical, health economics, and PRO data to justify brand value; guide evidence generation.
• Anticipate competitor moves with innovative market access strategies across the portfolio.
• Provide input into brand access initiatives and translate learnings into actions.

Skills

Leadership

Communication

Cross-functional

Data-driven

Market access

Payer strategy

Strategic pricing

Influence

Relationship

Project management

Education

Bachelor's degree

MBA / MPH / PharmD / HEOR

Job description

Overview

Reporting to the VP, Global Market Access, the candidate will act as the overall lead for global pricing & market access strategy for Alnylam’s Rare Disease portfolio, as well as for selected pipeline assets, bringing key learnings across the team and representing the franchise as part of the program development, market access and brand leadership teams to ensure consistency of approach in securing access for current and future products.

Reporting to the VP, Global Market Access, the candidate will act as the overall lead for global pricing & market access strategy for Alnylam’s Rare Disease portfolio, as well as for selected pipeline assets, bringing key learnings across the team and representing the franchise as part of the program development, market access and brand leadership teams to ensure consistency of approach in securing access for current and future products.

In addition, the candidate will be directly responsible for analyzing business cases and support decision making for all pricing requests for Alnylam’s Partner & Emerging Markets (P&EM), collaborating directly with Commercial Directors and external partners.

Lastly, the candidate will be responsible for managing the Global Pricing System (GPS) including quarterly price updates and reporting across the portfolio, creating efficiency in price approval process and lead change management to make GPS future-ready for the enterprise.

Key Responsibilities

• In collaboration with cross-functional teams at global and regional level, lead the development of strategic access plans for all in-line brands, new assets, pipeline products inclusive of access landscape development, payer segmentation, payer strategy, organized customer contracting and channel strategy, pricing, distribution, and value proposition development.
• Communicate access-specific strategies to internal business partners for incorporation into brand planning.
• Develop market access strategy from commercial view point with input from cross-functional teams.
• Help champion priority access initiatives with meaningful impact to the business to commercial leadership.
• Collaborate with Global and Regional Market Access Strategy counterparts to share learnings across business units that will drive franchise success.
• Serve as single-point-of-contact for all pricing strategy related discussions and guidance for P&EM business unit.
• Develop internal working partnerships with Regional Market Access, Value & Evidence Strategy Team, Pricing, Advocacy / Policy, and Legal to drive critical decision making and ensure proper execution.
• Lead the development of the payer value story, supported by credible clinical, health economics and PRO messages to justify brand value; interfaces with VESt team to guide evidence generation efforts that support payer value story development.
• Leverage understanding of the competitive landscape to anticipate and pre-empt future competitor moves by developing innovative strategies and tactics across Market Access.
• Provide input into above brand access initiatives and pull through learnings in branded access strategy.

Qualifications

• Bachelors Degree Required
• MBA, MPH, PharmD or Health Economics/Outcomes Research preferred
• 10 +years of commercial market access experience; 5+ years in rare disease
• Substantial US, EU & Emerging Market experience with market access strategies, launch pricing, contracting, reimbursement, and distribution concepts for specialty products
• Problem Solving & Innovation - Unstructured strategy development problems that can be logically linked to revenue and profit specific business cases. Examples include LOE strategies, launch strategies, pricing strategies and clinical development strategies.
• Proven ability to lead a high performing cross-functional team, and be ready to ‘roll-up-the-sleeves’ to get work done despite conflicting priorities.
• Strong written and verbal communication skills
• Experience in presenting and communicating to C-suite leaders with exceptional clarity and business focus.
• Strong business & scientific acumen, learning agility
• Ability to influence & build strong relationships in a matrix environment
• Ability to define, track, analyze key access performance measures and make data-driven decisions
• Ability to prioritize, pivot, and manage multiple projects simultaneously

U.S. Pay Range

210,000.00 - 284,100.00

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being.

• medical coverage
• dental coverage
• vision coverage
• life insurance
• disability insurance
• lifestyle reimbursement program
• flexible spending and health savings accounts
• 401(k)with a generous company match
• paid time off
• wellness days
• holidays
• two company-wide recharge breaks
• generous family resources and leave

Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

About Alnylam

We are the leader in RNAi therapeutics– a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.