Director, Enterprise Knowledge Graph & Semantics

Vertex Pharmaceuticals Inc (US)

Boston (MA)

Hybrid

USD 216,000 - 325,000

Full time

7 days ago
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Benefits offered by this job

Hybrid work policy

Job summary

Vertex is hiring an experienced engineering leader to build and operate the enterprise Knowledge Graph and semantic layer, unifying Vertex's data across clinical, research, regulatory, and commercial domains. The Director will define strategy, select technology, and lead a team delivering a traversable model for AI agents and analytics.

You will collaborate with ontology, data modeling, and application teams to onboard systems and ensure production readiness, reliability, and governance across

Qualifications

  • 10+ years of experience in data engineering, AI/ML, or advanced analytics with focus on knowledge graphs and semantic technologies.

Responsibilities

  • Design, build, and operate Vertex's enterprise knowledge graph across clinical, research, regulatory, and commercial domains.
  • Define the vertex's strategy for graph and semantic platform, including technology selection and architecture.
  • Partner with ontology and data modeling teams to translate domain ontologies into the graph.
  • Lead graph traversal and retrieval interfaces for AI agents and analytics.

Skills

Knowledge Graph
Semantic Layer
Graph Databases
Cross-Domain Data
AI & RAG
Leadership & Communication
Pharma/Life Sciences Context
Regulated Environment
Graph Query Languages
LLM Integration with Graphs

Tools

Cypher
SPARQL
Gremlin
GQL

Job description

Vertex is hiring an experienced engineering leader to build and operate the enterprise Knowledge Graph and semantic layer, unifying Vertex's data across clinical, research, regulatory, and commercial domains. The Director will define strategy, select technology, and lead a team delivering a traversable model for AI agents and analytics.

You will collaborate with ontology, data modeling, and application teams to onboard systems and ensure production readiness, reliability, and governance across

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