Director Data Management

Warman O'Brien; San Francisco (CA); On-site; USD 210,000 - 270,000; Full time

Job summary

Warman O'Brien is seeking a Director of Clinical Data Management to lead data strategy and delivery across its clinical programmes. This role combines strategic oversight with hands-on involvement, collaborating with Biometrics, Clinical Operations and Regulatory Affairs to ensure high-quality, analysis-ready data.

You will oversee data management across studies, manage CROs, guide DMPs, eCRFs, edit checks and data cleaning, and mentor the team to ensure timely regulatory submissions and robust

Qualifications

• 6+ years of clinical data management experience.
• 3+ years of people or project leadership experience.
• Hands-on EDC experience (Medidata Rave, Oracle InForm).
• Strong knowledge of regulatory requirements and trial operations.

Responsibilities

• Lead data management across multiple studies from setup to database lock.
• Oversee CROs and vendors to ensure quality and timely delivery.
• Guide DMPs, eCRFs, edit checks, data cleaning and reconciliation.
• Develop standards and optimise EDC systems for regulatory submissions.
• Mentor team and contribute to study design and planning.

Skills

Leadership

Data management

Communication

Education

Relevant degree

Tools

Medidata Rave

Oracle InForm

Job description

A clinical-stage biotech is seeking a Director of Clinical Data Management to lead data strategy and delivery across its clinical programmes.

This role combines strategic oversight with hands-on involvement, working closely with Biometrics, Clinical Operations and Regulatory Affairs to ensure high-quality, analysis-ready data.

Key responsibilities

• Lead data management across multiple clinical studies, from setup through database lock.
• Oversee CROs and vendors, ensuring quality and timely delivery.
• Guide DMPs, eCRFs, edit checks, data cleaning and reconciliation.
• Develop standards, optimise EDC systems and support regulatory submissions.
• Mentor team members and provide input into study design and planning.

Experience required

• Relevant degree and 6+ years of clinical data management experience within biotech, pharma or a CRO.
• 3+ years of people and/or project leadership experience.
• Hands‑on EDC experience, such as Medidata Rave or Oracle InForm.
• Strong knowledge of clinical trial operations and regulatory requirements.
• Collaborative leadership style with strong communication and vendor management skills.