Director, Data & AI Risk Management

AstraZeneca; Gaithersburg (MD); Hybrid; USD 153,000 - 230,000; Full time

Benefits offered by this job

Health insurance

retirement plan

Paid time off

Job summary

AstraZeneca in the United States seeks a Director, Data & AI Risk Management to lead enterprise risk activities, identify, assess, govern, report, and reduce Data & AI risk across regulatory compliance, data protection, and AI governance.

Reporting to the Senior Director, Data & AI Risk Management, the role partners with Data & AI Trust & Assurance and business functions to translate complex risk expectations into clear decisions, measurable improvements, and proactive risk posture management at

Qualifications

• Significant experience in risk management, assurance, governance, regulatory compliance, or second-line oversight within a complex, global organisation.
• Demonstrated experience assessing and managing data, technology, digital, and/or AI risks and translating complex issues into pragmatic business decisions.
• Strong project leadership and project management capability across cross-functional and matrixed teams.
• Experience providing risk advisory or consulting support, including risk appetite, mitigation, escalation, and risk acceptance discussions.
• Working knowledge of regulatory and compliance requirements such as US Data Security Program, EU AI Act, GDPR, or similar frameworks.
• Experience with governance forums, executive reporting, risk indicators, dashboards, or Enterprise Risk Management processes.
• Excellent written and verbal communication with ability to influence senior stakeholders.

Responsibilities

• Provide trusted risk advisory, consulting, and risk appetite support across Data & AI risks.
• Translate complex regulatory requirements into clear risk positions, decisions, and actions.
• Lead priority initiatives across Data & AI Trust and Assurance, including regulatory compliance programmes.
• Develop dashboards and narratives to improve visibility of Data & AI risk posture.
• Collaborate with Legal, Compliance, Privacy, Cyber Security, and other risk teams to align risk approaches.
• Support enterprise risk management reporting for senior leadership and governance bodies.

Skills

Risk management

Governance

Regulatory compliance

Data & AI risk

Executive reporting

Stakeholder management

Cross-functional leadership

Education

Bachelor's degree in Business Administration or related discipline

Job description

We're building a connected, end-to-end Enterprise AI engine - uniting data foundations, AI technology, process reinvention, and business-facing AI to accelerate results across the whole value chain. Success depends on being exceptional connectors: you'll actively leverage existing capabilities, celebrate and promote reuse, export breakthrough ideas across geographies and functions, and obsess over scaling impact rather than building in isolation. If you thrive in high-collaboration environments where your role is to turn complex, cross-functional problems into reusable, enterprise-wide capabilities - and where the measure of success is adoption and scale, not just innovation - you'll have the platform (and sponsorship) to make it real.

The Director, Data & AI Risk Management leads and delivers enterprise risk management activities that help AstraZeneca identify, assess, govern, report, and reduce Data & AI risk.

The role provides practical risk advisory, consulting, governance, and risk appetite support across regulatory compliance, data protection, AI governance, and related risk domains.

Reporting to the Senior Director, Data & AI Risk Management, the Director partners across Data & AI Trust and Assurance and with business and enabling functions to translate complex risk and regulatory expectations into clear decisions, proportionate mitigations, and measurable improvements in risk posture.

The role also leads cross-functional projects and supports enterprise governance forums and Enterprise Risk Management reporting, enabling responsible and confident use of Data & AI at scale.

Typical Accountabilities

• Provide trusted risk advisory, consulting, and risk appetite support across Data & AI risks, helping stakeholders make timely, proportionate, and well-informed decisions.
• Provide governance and business analysis support across regulatory compliance, data protection, AI governance, and other Data & AI risk areas, translating complex requirements into clear risk positions, decisions, and actions.
• Lead and/or project manage priority initiatives across Data & AI Trust and Assurance, irrespective of team boundaries, including Standards and Controls rollout and regulatory compliance programmes covering requirements such as the US Data Security Program, EU AI Act, European Health Data Space, and other emerging obligations.
• Improve visibility of Data & AI risk posture by developing clear narratives, indicators, dashboards, and insights on material exposures, trends, mitigations, residual risk, and progress against appetite.
• Engage business and functional stakeholders to build relationships and understand risk exposure, challenge the adequacy of mitigations, agree pragmatic remediation, and help drive residual risk and overall risk posture down.
• Lead selected aspects of Data & AI risk aggregation, analysis, and reporting for Enterprise Risk Management, senior leadership, and governance bodies.
• Facilitate risk assessments, workshops, and decision forums for complex or novel Data & AI use cases, balancing enablement, compliance, and protection of patients, the company, and its information and intellectual property.
• Synthesize complex issues into concise, executive-ready narratives; anticipate stakeholder concerns; navigate ambiguity; and influence decisions in high-stakes forums.
• Partner with Regulatory Intelligence, Legal, Compliance, Privacy, Cyber Risk, Enterprise Risk Management, Data Offices, and risk teams in R&D, Operations, Commercial, Enabling Units, and other business functions to align risk approaches and accountabilities.
• Work across Data & AI Trust and Assurance teams to accomplish shared goals, resolve cross-cutting issues, and deliver integrated outcomes across policy, standards and controls, assurance, monitoring, risk, and regulatory readiness.
• Identify opportunities to simplify and continuously improve Data & AI risk management processes, governance, reporting, and stakeholder experience while preserving effective oversight.
• Promote a culture of responsible, compliant, and value-focused use of Data & AI, demonstrating AstraZeneca values in all interactions.

Essential

Education, Qualifications, Skills, and Experience

• Bachelor's degree in business administration, Risk Management, Information/Data Science, Informatics, Computer Science, Economics, Law, or a related discipline, or equivalent relevant experience.
• Significant experience in risk management, assurance, governance, regulatory compliance, or second-line oversight within a complex, global organisation.
• Demonstrated experience assessing and managing data, technology, digital, and/or AI risks and translating complex issues into pragmatic business decisions.
• Strong project leadership and project management capability, including delivery through cross-functional and matrixed teams, such as Regulatory Compliance, areas of organisational risk, AI governance, or related disciplines.
• Experience providing risk advisory or consulting support, including risk appetite, mitigation, escalation, and risk acceptance discussions.
• Working knowledge of relevant Data & AI regulatory and compliance requirements, such as the US Data Security Program, EU AI Act, European Health Data Space, GDPR, GxP, NIS2, or comparable frameworks.
• Experience with governance forums, executive reporting, risk indicators, dashboards, or Enterprise Risk Management processes.
• Strong business analysis, facilitation, and problem-solving skills, with the ability to structure ambiguity and establish clear ownership and actions. This includes working across domains such as regulatory compliance, data protection, AI governance, or related disciplines to translate requirements into clear risk positions, decisions, accountabilities, and actions.
• Demonstrated experience developing risk reporting to support senior management decision-making.
• Proven ability to build partnerships across Legal, Compliance, Privacy, Cyber Security, Enterprise Risk Management, Data Offices, technology, and business functions.
• Excellent written and verbal communication, with the credibility to influence senior stakeholders and present concise, decision-oriented recommendations.
• Strong collaboration, negotiation, and change leadership skills, with a practical, proportionate, and enablement-focused mindset.

Desirable

• Master’s degree or advanced qualification in Business Administration, Risk Management, Information/Data Science, Informatics, Computer Science, Economics, Law, or a related discipline.
• Experience in life sciences, healthcare, or another highly regulated industry.
• Practical knowledge of ISO/IEC 42001, the NIST AI Risk Management Framework, or recognised enterprise risk and control frameworks.
• Data, AI, privacy, compliance, audit, governance, or risk management education and professional certifications.
• Experience implementing or assessing standards and controls and linking regulatory obligations, risks, controls, assurance, and reporting.
• Knowledge of key pharmaceutical business processes across R&D, Operations, Commercial, and Enabling Units.

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.

The annual base pay (or hourly rate of compensation) for this position ranges from $153,480.80 - $230,221.20 USD . Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

#EAI

Date Posted

25-Sept-2026

Closing Date

02-Oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.