Director, CMC Digital Strategy & Portfolio Execution

RXinsider LTD.; Cambridge (MA); On-site; USD 167,000 - 301,000; Full time

Benefits offered by this job

Competitive healthcare

Well-being resources

Family planning benefits

Generous paid time off

Savings and investments

Location-specific perks

Job summary

Moderna is seeking a Director of CMC Digital Operations and Strategic Portfolio Management to own and drive a defined portfolio of strategic digital initiatives. You will align Digital, CMC, TPM, Finance, and Operations to deliver measurable outcomes and enable predictable delivery across cross-CMC programs.

In this role, you will design and govern the portfolio operating model, build executive dashboards, manage risks, dependencies, and multi-vendor delivery, and translate complex roadmaps into

Qualifications

• 12+ years of experience in digital operations, IT, technical program management, portfolio management, or digital strategy execution.
• BA/BS degree in Information Technology, Business Administration, Life Sciences, Engineering, or a related field.
• Advanced degree (MA/MS/MBA) in Information Technology, Business Administration, Life Sciences, Engineering, or a related field.

Responsibilities

• Own and define the operational delivery of a defined CMC Digital portfolio, translating Digital and CMC priorities into clear 1–2 year outcomes, OKRs, roadmaps, and execution plans.
• Lead planning and governance rhythms across the portfolio, including prioritization, dependency and risk reviews, steering forums, decision records, and executive-ready portfolio updates.
• Partner with Digital, CMC, TPM, Finance, Operations, and external partners to ensure initiatives are defined, sequenced, resourced, measured, and aligned to business value.
• Drive predictable delivery across cross-CMC digital initiatives by identifying systemic blockers, escalating issues with clear options, and ensuring durable follow-through.
• Co-lead the design and continuous improvement of the portfolio operating model, including intake, prioritization, capacity planning, value tracking, documentation, and runbook standards.
• Build and maintain executive-facing dashboards and portfolio narratives that connect strategy, risk, investment, delivery health, and business impact.
• Act as a strategic liaison between Digital and senior CMC stakeholders, translating complex technical roadmaps and program interdependencies into clear value stories and decision points.
• Lead cross-functional working groups and stakeholder engagement mechanisms that promote alignment, transparency, accountability, and best-practice sharing across teams.
• Drive resource and capacity planning across internal teams and external partners; manage multi-vendor delivery models and optimize for cost, quality, speed, and risk.
• Partner with Finance and Operations to track budgets, support investment trade-off discussions, and ensure portfolio delivery aligns with Moderna’s enterprise goals.
• Embed security, privacy, compliance, and audit-ready practices into portfolio execution, partnering with appropriate teams to manage risk and evidence requirements.
• Use data-driven KPIs and outcome metrics to monitor portfolio performance, identify improvement opportunities, and steer operational decisions.
• Communicate clearly during change, incidents, and portfolio shifts, helping stakeholders understand priorities, trade-offs, risks, and expected outcomes.

Job description

Moderna is seeking a Director of CMC Digital Operations and Strategic Portfolio Management to own and drive a defined portfolio of strategic digital initiatives. You will align Digital, CMC, TPM, Finance, and Operations to deliver measurable outcomes and enable predictable delivery across cross-CMC programs.

In this role, you will design and govern the portfolio operating model, build executive dashboards, manage risks, dependencies, and multi-vendor delivery, and translate complex roadmaps into