Director, Clinical Scientist – Neuromuscular Therapies

dynetherapeutics; Waltham (MA); On-site; USD 180,000 - 280,000; Full time

Job summary

Dyne Therapeutics in Waltham, MA is seeking a Director, Clinical Scientist to lead scientific strategy and execution of rare neuromuscular disease programs. You will partner with Clinical Development Lead and cross-functional teams to advance high-quality studies.

The role requires independent leadership, strong clinical development judgment, and the ability to translate data into regulatory and external communications.

Responsibilities

• Lead or contribute as clinical science lead for assigned studies, partnering with the study medical director to support strategy, design, execution, data interpretation, and reporting.
• Provide scientific input into study design, population, eligibility, endpoints, biomarkers, assessments, and data collection strategies to ensure trials are sound and feasible.
• Interpret emerging clinical data and translate findings into recommendations for study conduct, governance discussions, regulatory interactions, and external communications.
• Maintain current knowledge of rare diseases, neuromuscular disease, genetic medicine, oligonucleotide therapeutics, trial innovation, regulatory expectations, and literature.

Job description

Dyne Therapeutics in Waltham, MA is seeking a Director, Clinical Scientist to lead scientific strategy and execution of rare neuromuscular disease programs. You will partner with Clinical Development Lead and cross-functional teams to advance high-quality studies.

The role requires independent leadership, strong clinical development judgment, and the ability to translate data into regulatory and external communications.