Director, Clinical Pharmacology & Translational Modeling

Beam Therapeutics Inc.; Cambridge (MA); On-site; USD 180,000 - 260,000; Full time

Job summary

Beam Therapeutics Inc. seeks an Associate Director/Director of Clinical Pharmacology to advance a growing portfolio of gene/base editing therapeutics.

The role emphasizes PK/PD modeling, translational science, and model-informed drug development integrated into study design and regulatory documents. The candidate will lead pharmacometrics activities, mentor junior scientists, and collaborate across cross-functional teams to drive decision-making and program strategy in a highly matrixed

Qualifications

• Ph.D. in Pharmacokinetics, Pharmacology, Pharmaceutics or related field with 3–10 years in pharma.
• Hands-on pharmacometrics application to drug development required.
• Expertise in PK/PD, ADME concepts, and clinical pharmacology.
• Experience with Phoenix WinNonLin, NONMEM and R for modeling and data visualization.

Responsibilities

• Build out and lead the Clinical Pharmacology function, including staffing and modeling infrastructure.
• Operationalize model-based drug development and regulatory guidance.
• Lead modeling projects and coordinate cross-discipline activities.
• Conduct PK/PKPD analyses using nonclinical and clinical data.

Skills

Pharmacokinetics

Pharmacology

Pharmacometrics

PK/PD modeling

R

Communication skills

Mentoring

Education

PhD in Pharmacokinetics

MD/PharmD with equivalent

Tools

Phoenix WinNonLin

NONMEM

R

Job description

Beam Therapeutics Inc. seeks an Associate Director/Director of Clinical Pharmacology to advance a growing portfolio of gene/base editing therapeutics.

The role emphasizes PK/PD modeling, translational science, and model-informed drug development integrated into study design and regulatory documents. The candidate will lead pharmacometrics activities, mentor junior scientists, and collaborate across cross-functional teams to drive decision-making and program strategy in a highly matrixed