Data Science Neuroscience PhD Co-op

6084-Janssen Research & Development, LLC Legal Entity; Cambridge (MA); On-site; USD 32,000 - 72,000; Full time

Benefits offered by this job

Medical benefits

Sick time benefits

Retirement plan

Job summary

Johnson & Johnson Innovative Medicine seeks a highly motivated PhD Co-op to join the Neuroscience DDSAI team for Spring 2027. You will build a large single-cell and multi-omics atlas for neuropsychiatry and develop computational approaches to uncover disease mechanisms and nominate therapeutic targets.

Responsibilities include cell-cell communication analyses, AI/ML-driven target nomination, and cross-functional collaboration to translate discoveries into portfolio decisions.

Qualifications

• Currently pursuing a PhD in Computational Biology, Bioinformatics, Systems Biology, Biomedical Sciences, Neuroscience, Computer Science, or Data Science.
• Strong programming skills in Python and/or R (incl. AI-assisted coding).
• Experience with high-dimensional multimodal datasets (scRNA-seq, ATAC-seq, proteomics, genomics).
• Strong scientific communication and presentation skills.

Responsibilities

• Benchmark and apply methods to map cell-cell communication networks in schizophrenia and bipolar disorder.
• Identify disruptions in ligand-receptor interactions across cell populations.
• Apply AI/ML on single-cell atlases to nominate targets and integrate multi-omics data.
• Collaborate across Data Science, Neuropsychiatry Discovery, and translational biology teams to advance target discovery.

Skills

Python

R

AI/ML

Communication

Education

PhD in Computational Biology or related field

Tools

LIANA+

Cellchat

MultiNicheNet

Job description

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Job Function: Career Programs Job Sub Function: Non-LDP Intern/Co-Op Job Category: Career Program All Job Posting Locations: Cambridge, Massachusetts, United States of America

Johnson & Johnson Innovative Medicine is seeking a highly motivated PhD Co-op to join the Neuroscience DDSAI team for Spring 2027. This role offers a unique opportunity to work within the team building out a large single-cell and multi-omics atlas for neuropsychiatry. The successful candidate will develop and apply advanced computational approaches to understand cell-type-specific disease mechanisms, map cell-cell communication networks, identify dysregulated signaling pathways in neuropsychiatry, and nominate novel therapeutic targets for neuropsychiatry discovery programs at J&J. In addition to cell-cell communication analyses, the candidate will explore cutting-edge AI/ML approaches that leverage large-scale single-cell, genetic, transcriptomic, proteomic, and multimodal datasets to systematically prioritize actionable therapeutic targets and pathways.

Key Responsibilities

Cell-Cell Communication and Disease Biology

• Benchmark and apply state-of-the-art methods to map cell-cell communication networks in schizophrenia and bipolar disorder.
• Identify disease-associated disruptions in ligand-receptor interactions and intercellular biological circuits across cell populations.
• Generate disease-specific cellular interaction maps to uncover novel mechanisms and target discovery opportunities in neuropsychiatric disorders.

AI/ML-driven applications on single-cell atlases for target nomination

• Apply cutting-edge AI and single-cell analytics to uncover disease-associated cell states and pathways in schizophrenia and bipolar disorder.
• Leverage machine learning, network biology, and foundation models to identify novel therapeutic targets and disease mechanisms.
• Integrate single-cell discoveries with orthogonal multi-omics data to support precision target identification in neuropsychiatry.

Drive translational impact through cross-functional collaboration

• Collaborate with multidisciplinary teams spanning Data Science, Precision Measures, and Neuropsychiatry Discovery to advance target discovery programs.
• Present findings to scientific leaders and contribute to publications, posters, and presentations at internal and external scientific conferences.

Target Hire Date: 01/4/2027

Target End Date: 6/30/2027

Qualifications

Required

• Currently pursuing a PhD in one of the following or a related quantitative discipline: Computational Biology, Bioinformatics, Systems Biology, Biomedical Sciences, Neuroscience, Computer Science, Data Science.
• Strong programming skills in Python and/or R (including effective use of AI-assisted coding).
• Experience analyzing high-dimensional multimodal biological datasets, with a preference for single-cell RNASeq, ATACSeq, proteomics, and genomics datasets. Familiarity with machine learning, statistics, and computational biology methods.
• Strong scientific communication and presentation skills.

Preferred

• Experience with graph analytics, network biology, knowledge graphs, or generative AI methods.
• Familiarity with cell-cell communication modeling tools (LIANA+, Cellchat, MultiNicheNet etc.), pathway analysis, and systems biology.

Candidate Eligibility Requirements

Candidates must:

• Be authorized to work in the US without current or future sponsorship requirements.
• Remain actively enrolled in their academic program throughout the entire internship period.
• Be available to work 40 hours per week during the internship.
• Should have a minimum GPA of 3

Permanently authorized to work in the U.S., must not require sponsorship of an employment visa (e.g., H-1B or green card) at the time of application or in the future. Students currently on CPT, OPT, or STEM OPT usually requires future sponsorship for long term employment and does not meet the requirements for this program unless eligible for an alternative long-term status that does not require company sponsorship.

What you will gain

• Hands‑on experience applying state‑of‑the‑art AI and computational biology approaches to real‑world drug discovery challenges.
• Exposure to one of the largest industry efforts in Neuropsychiatry data science, multi‑omics, and precision medicine.
• Mentorship from multidisciplinary experts spanning data science, neuroscience, genomics, translational biology, and drug discovery.
• Opportunity to contribute directly to therapeutic target nomination and portfolio decisions for future Neuropsychiatry medicines.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers . Internal employees contact AskGS to be directed to your accommodation resource.

The anticipated base pay range for this position is : $23.50/hr to $52.50/hr

Additional Description for Pay Transparency: The expected pay range for this position is between $23.50 per hour and $52.50 per hour but will be based on candidate's program year, discipline, degree and/or experience.

Benefits

• Co-Ops/Interns are eligible to participate in Company sponsored employee medical benefits in accordance with the terms of the plan.
• Co-Ops and Interns are eligible for the following sick time benefits: up to 40 hours per calendar year; for employees who reside in the State of Washington, up to 56 hours per calendar year.
• Co-Ops and Interns are eligible to participate in the Company’s consolidated retirement plan (pension).
• For additional general information on Company benefits, please go to: https://www.careers.jnj.com/employee-benefits

This job posting is anticipated to close on [6/30/2027]. The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at https://www.jnj.com/.